Detailed information NTG0859160

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V80_RS09540
• Genome accession: NZ_CP130515
• Coordinates: 1948924..1949967 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA28-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1943924..1954967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V80_RS09510	-	1944345..1945601 (-)	1257	WP_075583716.1	aminopeptidase	-
Q3V80_RS09515	-	1945604..1945804 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V80_RS09520	-	1945951..1946415 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V80_RS09525	-	1946422..1946697 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V80_RS09530	-	1946975..1948192 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V80_RS09535	vraR	1948305..1948934 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V80_RS09540	vraS	1948924..1949967 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V80_RS09545	liaF	1949964..1950665 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V80_RS09550	-	1950680..1951066 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V80_RS09555	map	1951283..1952041 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V80_RS09560	-	1952570..1953556 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V80_RS09565	-	1953987..1954400 (-)	414	WP_001670387.1	hypothetical protein	-
Q3V80_RS09570	-	1954429..1954539 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859160 Q3V80_RS09540 WP_001017131.1 1948924..1949967(-) (vraS) [Staphylococcus aureus strain SA28-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859160 Q3V80_RS09540 WP_001017131.1 1948924..1949967(-) (vraS) [Staphylococcus aureus strain SA28-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1