Detailed information NTG0859119

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V79_RS09595
• Genome accession: NZ_CP130513
• Coordinates: 1960039..1961082 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA29-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1955039..1966082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V79_RS09565	-	1955467..1956723 (-)	1257	WP_001793428.1	aminopeptidase	-
Q3V79_RS09570	-	1956726..1956926 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V79_RS09575	-	1957073..1957537 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V79_RS09580	-	1957544..1957819 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V79_RS09585	-	1958097..1959308 (+)	1212	WP_153906454.1	YihY/virulence factor BrkB family protein	-
Q3V79_RS09590	vraR	1959420..1960049 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V79_RS09595	vraS	1960039..1961082 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V79_RS09600	liaF	1961079..1961780 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V79_RS09605	-	1961795..1962181 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V79_RS09610	map	1962398..1963156 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V79_RS09615	-	1963687..1964673 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
Q3V79_RS09620	-	1965163..1965576 (-)	414	WP_001837236.1	hypothetical protein	-
Q3V79_RS09625	-	1965605..1965716 (-)	112	Protein_1858	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859119 Q3V79_RS09595 WP_001017131.1 1960039..1961082(-) (vraS) [Staphylococcus aureus strain SA29-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859119 Q3V79_RS09595 WP_001017131.1 1960039..1961082(-) (vraS) [Staphylococcus aureus strain SA29-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1