Detailed information NTG0859030

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V69_RS09480
• Genome accession: NZ_CP130510
• Coordinates: 1928987..1930030 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA31-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1923987..1935030

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V69_RS09450	-	1924408..1925664 (-)	1257	WP_001795108.1	aminopeptidase	-
Q3V69_RS09455	-	1925667..1925867 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V69_RS09460	-	1926014..1926478 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V69_RS09465	-	1926485..1926760 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V69_RS09470	-	1927038..1928255 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V69_RS09475	vraR	1928368..1928997 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V69_RS09480	vraS	1928987..1930030 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V69_RS09485	liaF	1930027..1930728 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V69_RS09490	-	1930743..1931129 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V69_RS09495	map	1931346..1932104 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V69_RS09500	-	1932662..1933621 (+)	960	WP_234718382.1	aromatic acid exporter family protein	-
Q3V69_RS09505	-	1934052..1934465 (-)	414	WP_001557448.1	hypothetical protein	-
Q3V69_RS09510	-	1934494..1934604 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=859030 Q3V69_RS09480 WP_001017131.1 1928987..1930030(-) (vraS) [Staphylococcus aureus strain SA31-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=859030 Q3V69_RS09480 WP_001017131.1 1928987..1930030(-) (vraS) [Staphylococcus aureus strain SA31-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1