Detailed information NTG0858901

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V82_RS09730
• Genome accession: NZ_CP130507
• Coordinates: 1983769..1984812 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA34-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1978769..1989812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V82_RS09700	-	1979190..1980446 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V82_RS09705	-	1980449..1980649 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V82_RS09710	-	1980796..1981260 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V82_RS09715	-	1981267..1981542 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V82_RS09720	-	1981820..1983037 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V82_RS09725	vraR	1983150..1983779 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V82_RS09730	vraS	1983769..1984812 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V82_RS09735	liaF	1984809..1985510 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V82_RS09740	-	1985525..1985911 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V82_RS09745	map	1986128..1986886 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V82_RS09750	-	1987415..1988401 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V82_RS09755	-	1988834..1989247 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V82_RS09760	-	1989276..1989386 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=858901 Q3V82_RS09730 WP_001017131.1 1983769..1984812(-) (vraS) [Staphylococcus aureus strain SA34-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=858901 Q3V82_RS09730 WP_001017131.1 1983769..1984812(-) (vraS) [Staphylococcus aureus strain SA34-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1