Detailed information NTG0858857

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V81_RS09160
• Genome accession: NZ_CP130505
• Coordinates: 1891724..1892767 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA35-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1886724..1897767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V81_RS09130	-	1887145..1888401 (-)	1257	WP_001795108.1	aminopeptidase	-
Q3V81_RS09135	-	1888404..1888604 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V81_RS09140	-	1888751..1889215 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V81_RS09145	-	1889222..1889497 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V81_RS09150	-	1889775..1890992 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
Q3V81_RS09155	vraR	1891105..1891734 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
Q3V81_RS09160	vraS	1891724..1892767 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V81_RS09165	liaF	1892764..1893465 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V81_RS09170	-	1893480..1893866 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V81_RS09175	map	1894083..1894841 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V81_RS09180	-	1895399..1896358 (+)	960	WP_234718382.1	aromatic acid exporter family protein	-
Q3V81_RS09185	-	1896789..1897202 (-)	414	WP_001557448.1	hypothetical protein	-
Q3V81_RS09190	-	1897231..1897341 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=858857 Q3V81_RS09160 WP_001017131.1 1891724..1892767(-) (vraS) [Staphylococcus aureus strain SA35-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=858857 Q3V81_RS09160 WP_001017131.1 1891724..1892767(-) (vraS) [Staphylococcus aureus strain SA35-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1