Detailed information NTG0858772

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V87_RS10105
• Genome accession: NZ_CP130502
• Coordinates: 2028036..2029079 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA37-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2023036..2034079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V87_RS10075	-	2023457..2024713 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V87_RS10080	-	2024716..2024916 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V87_RS10085	-	2025063..2025527 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V87_RS10090	-	2025534..2025809 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V87_RS10095	-	2026087..2027304 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V87_RS10100	vraR	2027417..2028046 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V87_RS10105	vraS	2028036..2029079 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V87_RS10110	liaF	2029076..2029777 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V87_RS10115	-	2029792..2030178 (-)	387	WP_001110179.1	hypothetical protein	-
Q3V87_RS10120	map	2030395..2031153 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V87_RS10125	-	2031682..2032668 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V87_RS10130	-	2033101..2033514 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V87_RS10135	-	2033543..2033653 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=858772 Q3V87_RS10105 WP_001017131.1 2028036..2029079(-) (vraS) [Staphylococcus aureus strain SA37-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=858772 Q3V87_RS10105 WP_001017131.1 2028036..2029079(-) (vraS) [Staphylococcus aureus strain SA37-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1