Detailed information NTG0858729

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q3V71_RS09960
• Genome accession: NZ_CP130501
• Coordinates: 2013651..2014694 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA38-SX
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2008651..2019694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V71_RS09930	-	2009072..2010328 (-)	1257	WP_078065149.1	aminopeptidase	-
Q3V71_RS09935	-	2010331..2010531 (-)	201	WP_000180460.1	DUF1128 family protein	-
Q3V71_RS09940	-	2010678..2011142 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
Q3V71_RS09945	-	2011149..2011424 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
Q3V71_RS09950	-	2011702..2012919 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
Q3V71_RS09955	vraR	2013032..2013661 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
Q3V71_RS09960	vraS	2013651..2014694 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
Q3V71_RS09965	liaF	2014691..2015392 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
Q3V71_RS09970	-	2015407..2015793 (-)	387	WP_111058724.1	hypothetical protein	-
Q3V71_RS09975	map	2016010..2016768 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
Q3V71_RS09980	-	2017297..2018283 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
Q3V71_RS09985	-	2018716..2019129 (-)	414	WP_025174552.1	hypothetical protein	-
Q3V71_RS09990	-	2019158..2019268 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=858729 Q3V71_RS09960 WP_001017131.1 2013651..2014694(-) (vraS) [Staphylococcus aureus strain SA38-SX]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=858729 Q3V71_RS09960 WP_001017131.1 2013651..2014694(-) (vraS) [Staphylococcus aureus strain SA38-SX]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1