Detailed information NTG0858694

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: Q3V71_RS00205
• Genome accession: NZ_CP130501
• Coordinates: 47217..48566 (-)
• Length: 449 a.a.
• NCBI ID: WP_000815640.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain SA38-SX
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	38802..54118	47217..48566	within	0

Gene organization within MGE regions

Location: 38802..54118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3V71_RS00165	mecA	38802..40811 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
Q3V71_RS00170	-	40908..41894 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
Q3V71_RS00175	-	41866..42126 (+)	261	WP_001549961.1	type I restriction enzyme endonuclease domain-containing protein	-
Q3V71_RS00180	-	42117..43724 (-)	1608	Protein_33	IS1182 family transposase	-
Q3V71_RS00185	-	43776..44282 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
Q3V71_RS00190	-	44297..44608 (-)	312	WP_000700851.1	DUF960 family protein	-
Q3V71_RS00195	-	44695..45045 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
Q3V71_RS00200	ccrB	45567..47195 (-)	1629	WP_001186608.1	cassette chromosome recombinase CcrB	Machinery gene
Q3V71_RS00205	ccrA	47217..48566 (-)	1350	WP_000815640.1	cassette chromosome recombinase CcrA	Machinery gene
Q3V71_RS00210	-	48800..50587 (-)	1788	WP_000122620.1	cassette chromosome replicative helicase	-
Q3V71_RS00215	-	50587..50877 (-)	291	WP_001036438.1	cassette chromosome ssDNA-binding protein	-
Q3V71_RS00220	-	51016..52065 (+)	1050	WP_000613248.1	hypothetical protein	-
Q3V71_RS00225	-	52628..54118 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52663.34 Da
• Isoelectric Point: 9.9639

>NTDB_id=858694 Q3V71_RS00205 WP_000815640.1 47217..48566(-) (ccrA) [Staphylococcus aureus strain SA38-SX]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=858694 Q3V71_RS00205 WP_000815640.1 47217..48566(-) (ccrA) [Staphylococcus aureus strain SA38-SX]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (4-147)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Recombinase (Recombinase) (169-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.55	100	0.976
ccrA	Staphylococcus aureus COL	75.947	100	0.759