Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   STYK_RS10010 Genome accession   NZ_AP024523
Coordinates   2010142..2012574 (-) Length   810 a.a.
NCBI ID   WP_261804991.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005142..2017574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS09985 (STYK_19180) - 2006092..2006790 (-) 699 WP_261804988.1 hypothetical protein -
  STYK_RS09990 (STYK_19190) - 2007069..2007299 (+) 231 WP_004255357.1 hypothetical protein -
  STYK_RS09995 (STYK_19200) - 2007372..2008145 (-) 774 WP_261804989.1 NUDIX hydrolase -
  STYK_RS10000 (STYK_19210) pnuC 2008147..2008926 (-) 780 WP_000736875.1 nicotinamide riboside transporter PnuC -
  STYK_RS10005 (STYK_19220) - 2008936..2009994 (-) 1059 WP_261804990.1 AAA family ATPase -
  STYK_RS10010 (STYK_19230) clpC 2010142..2012574 (-) 2433 WP_261804991.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  STYK_RS10015 (STYK_19240) - 2012576..2013034 (-) 459 WP_024057371.1 CtsR family transcriptional regulator -
  STYK_RS10020 (STYK_19250) - 2013153..2013881 (-) 729 WP_261043618.1 ABC transporter ATP-binding protein -
  STYK_RS10025 (STYK_19260) - 2013881..2014888 (-) 1008 WP_261043617.1 ABC transporter substrate-binding protein -
  STYK_RS10030 (STYK_19270) - 2014926..2015684 (-) 759 WP_186822058.1 ABC transporter permease -
  STYK_RS10035 (STYK_19280) - 2015647..2015937 (-) 291 WP_045605281.1 thiamine-binding protein -
  STYK_RS10040 (STYK_19290) cbpD 2016191..2017309 (-) 1119 WP_045605283.1 choline binding-anchored murein hydrolase CbpD -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 90164.85 Da        Isoelectric Point: 5.8459

>NTDB_id=85775 STYK_RS10010 WP_261804991.1 2010142..2012574(-) (clpC) [Streptococcus toyakuensis strain TP1632]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPSEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAATTVQNKAKHVKADDSGLSLADKALIDGKWKQAAQLIAKEEEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELEAGSTLKIGV
KAGQLKFDIA

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=85775 STYK_RS10010 WP_261804991.1 2010142..2012574(-) (clpC) [Streptococcus toyakuensis strain TP1632]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTATATGGTTGCTGGCCATTTTGGAGCTCGTTACCTAGA
GTCTTGGCACTTGTTGATTGCTATGTCCAATCATAGTTACAGTGTAGCAGGGGCGACATTAAACGATTATCCATATGAGA
TGGACCGTTTAGAAGAGGTCGCGTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTT
TCTCATCGTTTGCAGGTCCTCTTTGATGAGGCGGAATATGTGGCGTCAGTGGTCCATGCTAAGGTGCTAGGGACGGAGCA
CGTCCTTTATGCGATTTTGCATGATGGAAATGCCTTGGCAACTCGTATCTTGGAGAGGGCTGGCTTTTCTTATGAAGACA
AGAAAGATCAGGTCAAGATTGCTGCCCTACGTCGAAATCTAGAAGAACGTGCAGGTTGGACTCGTGAAGACCTCAAGGCT
TTACGCCAACGTCATCGTACAGTAGCTGACAAGCAAAATTCTATGGCTAATATGATGGGCATGCCCCAGACTCCGAGTGG
TGGTCTCGAGGACTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATCGGTCGGGACAAGG
AAATCTCACGTATGATTCAAATCTTGAGTCGAAAGACCAAGAACAATCCTGTCTTGGTTGGGGATGCTGGTGTCGGGAAA
ACAGCCTTGGCGCTTGGGCTCGCTCAGCGTATTGCTAGTGGTGATGTACCTTCGGAAATGGCTAAGATGCGCGTGTTAGA
GCTTGATTTGATGAATGTCGTTGCAGGGACACGCTTCCGTGGTGACTTTGAAGAACGCATGAACAATATCATCAAGGATA
TTGAAGAAGATGGCCAAGTCATCCTCTTTATCGATGAACTTCATACCATCATGGGTTCTGGGAGTGGAATTGATTCGACT
CTGGATGCGGCCAACATCTTGAAGCCAGCCTTAGCGCGTGGAACTTTGAGAACAGTTGGTGCGACCACTCAGGAAGAATA
TCAAAAACACATCGAAAAAGACGCAGCTCTTTCTCGTCGTTTCGCCAAAGTTACGATTGAAGAGCCAAGTGTTGCAGACA
GCATGACCATTTTGCAAGGTTTGAAGGCGACTTATGAGAAACATCACCGTGTGCAAATCACAGATGAAGCAGTTGAAACA
GCTGTCAAGATGGCTCATCGTTATTTGACTAGTCGTCACTTGCCAGACTCTGCTATTGATCTCTTGGATGAAGCAGCAAC
AACAGTGCAAAATAAGGCTAAGCATGTAAAAGCAGACGATTCAGGTTTGAGTCTAGCTGACAAGGCCTTGATAGATGGTA
AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTGCCTGTCTATAAAGACTTGGTGACAGAGTCTGATATT
TTGACCACCTTGAGTCGCTTGTCAGGTATTCCAGTCCAAAAACTGACTCAGACTGATGCTAAGAAATACTTAAACTTGGA
AGCTGAACTGCACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCGATTCGCCGCAACCAGTCAG
GGATTCGTAGTCATAAGCGTCCGATTGGTTCCTTTATGTTCTTAGGGCCTACAGGTGTCGGGAAGACTGAATTGGCCAAG
GCTTTGGCGGAAGTTCTTTTTGACGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
CAGTCGTCTCAACGGAGCTCCTCCGGGTTATGTGGGCTACGAAGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAACAAAC
CATACTCTGTTCTCCTATTTGATGAGGTAGAAAAAGCCCACCCAGACATCTTTAATGTTCTCTTGCAGGTCTTGGATGAC
GGTGTCTTGACCGATAGTAAGGGACGCAAGGTTGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
AGCCCTTCGTGATGACAAGACTGTCGGATTTGGGGCAAAGGACATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT
TTGAAGAGCTAAAAAAGGCTTATAGACCTGAGTTTATTAACCGTATTGATGAAAAGGTGGTCTTCCATAGCCTGTCTAGC
GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAACCTTTAGTGGCAAGTTTGGCTGAAAAAGGTATTGACTTGAAATT
ACAAGCTTCAGCCCTGAAATTGTTGGCAAATCAAGGATATGACCCAGAGATGGGAGCTCGTCCACTTCGTAGAACCCTAC
AAACAGAAGTGGAAGACAAGTTGGCAGAACTTCTTCTCAAGGGAGAATTAGAGGCAGGCAGCACACTTAAGATTGGTGTC
AAAGCAGGCCAGTTAAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-139)

AAA domain (Cdc48 subfamily) (AAA_2)

(540-711)

AAA lid domain (AAA_lid_9)

(370-439)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(718-798)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

98.765

100

0.988
  clpC Streptococcus pneumoniae D39

98.765

100

0.988
  clpC Streptococcus pneumoniae TIGR4

98.765

100

0.988
  clpC Streptococcus mutans UA159

67.036

100

0.673
  clpC Streptococcus thermophilus LMD-9

65.971

100

0.663
  clpC Streptococcus thermophilus LMG 18311

65.848

100

0.662
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.678

100

0.5
  clpC Bacillus subtilis subsp. subtilis str. 168

45.241

99.877

0.452
  clpE Streptococcus mutans UA159

48.986

79.136

0.388
  clpE Streptococcus pneumoniae Rx1

47.152

78.025

0.368
  clpE Streptococcus pneumoniae D39

47.152

78.025

0.368
  clpE Streptococcus pneumoniae R6

47.152

78.025

0.368
  clpE Streptococcus pneumoniae TIGR4

45.639

79.259

0.362
  clpC Lactococcus lactis subsp. cremoris KW2

46.955

77.037

0.362

Multiple sequence alignment