Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   STYK_RS04250 Genome accession   NZ_AP024523
Coordinates   815406..817664 (-) Length   752 a.a.
NCBI ID   WP_261805303.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 810406..822664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS04235 (STYK_07810) ezrA 812411..814138 (+) 1728 WP_061654061.1 septation ring formation regulator EzrA -
  STYK_RS04240 (STYK_07820) - 814313..814612 (-) 300 WP_000767194.1 DUF1827 family protein -
  STYK_RS04245 (STYK_07830) - 814824..815276 (-) 453 WP_020902950.1 NUDIX hydrolase -
  STYK_RS04250 (STYK_07840) clpE 815406..817664 (-) 2259 WP_261805303.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  STYK_RS04255 (STYK_07850) - 817895..818125 (-) 231 WP_000443570.1 DUF1797 family protein -
  STYK_RS04260 (STYK_07860) - 818316..818999 (+) 684 WP_033686685.1 amino acid ABC transporter permease -
  STYK_RS04265 (STYK_07870) - 818999..819733 (+) 735 WP_023946442.1 amino acid ABC transporter ATP-binding protein -
  STYK_RS04270 (STYK_07880) - 819911..820771 (+) 861 WP_261097267.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  STYK_RS04275 (STYK_07890) - 820835..821656 (+) 822 WP_261805304.1 phosphate ABC transporter ATPase -
  STYK_RS04280 (STYK_07900) - 821670..822521 (+) 852 WP_261805305.1 NAD(P)H-hydrate dehydratase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83782.26 Da        Isoelectric Point: 5.2972

>NTDB_id=85741 STYK_RS04250 WP_261805303.1 815406..817664(-) (clpE) [Streptococcus toyakuensis strain TP1632]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNTLFKGITDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
IEKDLKAVMTSKGNIQIKSAKKAEVKTSEKEV

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=85741 STYK_RS04250 WP_261805303.1 815406..817664(-) (clpE) [Streptococcus toyakuensis strain TP1632]
ATGCTTTGTCAAAACTGTAAAATCAATGACTCAACAATTCATCTTTACACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTATAAGATTATCAAGACAGATCCTAACAATACCCTCTTTAAAGGTATTACGGATCTGAACAATC
GTGACTTTGATCCCTTTGGTGATTTCTTCAATGACCTAAACAATTTCAGGCCTTCTAACAATACTCCTCCGACTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAATGGCGGCTATGGTTCCCAAAATCGTGGACCTGCTCAAACTCCTCCACCAAG
CCAAGAAAAAGGCCTACTGGAAGAATTTGGTATCAACGTAACTGAAATTGCCCGTCGTGGAGATATTGACCCCGTTATTG
GGCGCGACGATGAGATTATCCGTGTCATAGAAATTCTCAATCGCAGAACCAAGAATAATCCTGTTCTTATCGGTGAACCA
GGTGTCGGAAAAACTGCCGTTGTCGAAGGTCTAGCTCAGAAAATAGTTGATGGAGATGTTCCCCATAAACTACAAGGAAA
ACAAGTCATCCGTCTGGATGTGGTTAGCCTAGTTCAAGGAACGGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAGGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTCGGTGCTGGTTCTGCG
GGCGATGGCAATATGGATGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGGGAACTGCAACTGGTCGGTGCCACTAC
CCTCAATGAATACCGTATCATTGAAAAAGATGCTGCCCTAGAGCGCCGTATGCAACCAGTTAAGGTCGATGAACCAACAG
TAGAAGAAACAATCACTATCCTCAAAGGGATTCAAAAGAAATACGAAGACTACCACCACGTTCAGTATACCGATGCTGCA
ATTGAAGCAGCTGCAACTCTTTCCAATCGCTACATCCAAGATCGCTTCTTGCCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAACTTGACCTTGAATTTTGTCGATCCTAAAGTGATTGATCAACGCTTGATTGAGGCTGAAAATC
TCAAGTCTCAAGCTACACGAGAAGAAGATTTTGAAAAGGCTGCCTACTTCCGCGACCAGATTGCCAAATATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAGGATACTCCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAGCAGAAAACCAA
TATCCCTGTTGGCGATTTGAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTTATTG
GGCAGGATGATGCAGTCGATAAGATTGCCAAGGCTATTCGCCGGAATCGTGTCGGACTTGGTACCCCTAACCGCCCAATT
GGAAGCTTCCTCTTTGTCGGACCAACTGGTGTCGGTAAGACAGAACTTTCCAAACAACTAGCCATTGAACTTTTTGGTTC
TGCTGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAAAAACACAGTGTGGCGAAATTAGTCGGTGCCCCTCCAG
GTTATGTCGGCTATGACGAGGCTGGGCAATTAACTGAAAAAGTCCGCCGCAATCCCTACTCTCTTATTCTCTTGGATGAA
GTAGAGAAAGCCCATCCAGATGTCATGCATATGTTCCTCCAGGTCTTGGACGATGGTCGTTTAACAGATGGACAAGGACG
TACCGTTAGCTTCAAGGACGCCATCATCATCATGACTTCAAATGCAGGTACAGGTAAGGCAGAAGCTAGCGTTGGATTTG
GTGCTGCTAGAGAAGGACGTACCAACTCTGTTCTTGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAAGATAACCTCCTTCAGATTGTCGAGCTTATGCTTGCAGATGTTAACAA
ACGTCTTTCTAGCAACAACATTCATTTGGATGTAACCGACAAGGTCAAGGAAAAATTGGTTGACCTTGGTTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGTACTATTCAAGACTATATTGAGGACGCAATCACTGACTACTACCTTGAAAATCCA
ATCGAAAAAGACCTCAAGGCAGTGATGACCAGCAAGGGTAACATTCAAATCAAATCTGCCAAAAAAGCTGAAGTAAAGAC
TTCTGAAAAAGAAGTATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(155-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)

AAA lid domain (AAA_lid_9)

(293-390)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-724)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

98.136

99.867

0.98
  clpE Streptococcus pneumoniae D39

98.136

99.867

0.98
  clpE Streptococcus pneumoniae R6

98.136

99.867

0.98
  clpE Streptococcus pneumoniae TIGR4

98.003

99.867

0.979
  clpE Streptococcus mutans UA159

83.333

99.734

0.831
  clpC Lactococcus lactis subsp. cremoris KW2

75.494

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

50.646

92.686

0.469
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.627

84.043

0.4
  clpC Streptococcus pneumoniae TIGR4

47.293

83.511

0.395
  clpC Streptococcus pneumoniae Rx1

46.91

83.91

0.394
  clpC Streptococcus pneumoniae D39

46.91

83.91

0.394
  clpC Streptococcus mutans UA159

46.593

83.91

0.391
  clpC Streptococcus thermophilus LMD-9

46.795

82.979

0.388
  clpC Streptococcus thermophilus LMG 18311

46.4

83.112

0.386

Multiple sequence alignment