Detailed information NTG0085612

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: QUE76_RS24265
• Genome accession: NZ_AP027419
• Coordinates: 4779141..4780166 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain EC476 isolate EC476
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4774141..4785166

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QUE76_RS24255 (MUTS6_46680)	rpmE	4776372..4776584 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
QUE76_RS24260 (MUTS6_46690)	priA	4776787..4778985 (+)	2199	WP_001330197.1	primosomal protein N'	Machinery gene
QUE76_RS24265 (MUTS6_46700)	cytR	4779141..4780166 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
QUE76_RS24270 (MUTS6_46710)	ftsN	4780258..4781217 (+)	960	WP_000068834.1	cell division protein FtsN	-
QUE76_RS24275 (MUTS6_46720)	hslV	4781310..4781840 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
QUE76_RS24280 (MUTS6_46730)	hslU	4781850..4783181 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
QUE76_RS24285 (MUTS6_46740)	menA	4783248..4784174 (+)	927	WP_001305044.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
QUE76_RS24290 (MUTS6_46750)	rraA	4784267..4784752 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
QUE76_RS24295 (MUTS6_46760)	zapB	4784837..4785082 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=85612 QUE76_RS24265 WP_000644904.1 4779141..4780166(+) (cytR) [Escherichia coli strain EC476 isolate EC476]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=85612 QUE76_RS24265 WP_000644904.1 4779141..4780166(+) (cytR) [Escherichia coli strain EC476 isolate EC476]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACCGTTCATATAGACAATCTGACCGCCGCATTTGATGCGGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGTGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628