Detailed information NTG0856113

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: QZH48_RS03025
• Genome accession: NZ_CP129879
• Coordinates: 591974..594424 (+)
• Length: 816 a.a.
• NCBI ID: WP_270220371.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain CAB701
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 586974..599424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZH48_RS03000 (QZH48_03000)	-	587736..588248 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
QZH48_RS03005 (QZH48_03005)	rpoE	588465..589028 (+)	564	WP_003129551.1	DNA-directed RNA polymerase subunit delta	-
QZH48_RS03010 (QZH48_03010)	mltG	589165..590817 (+)	1653	WP_038599604.1	endolytic transglycosylase MltG	-
QZH48_RS03015 (QZH48_03015)	greA	590878..591351 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
QZH48_RS03020 (QZH48_03020)	-	591529..591984 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
QZH48_RS03025 (QZH48_03025)	clpC	591974..594424 (+)	2451	WP_270220371.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QZH48_RS03030 (QZH48_03030)	raiA	594559..595116 (+)	558	WP_098394069.1	ribosome-associated translation inhibitor RaiA	-
QZH48_RS03035 (QZH48_03035)	eno	595304..596605 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
QZH48_RS03040 (QZH48_03040)	-	596720..597391 (-)	672	WP_038599611.1	ABC transporter ATP-binding protein	-
QZH48_RS03045 (QZH48_03045)	-	597394..598467 (-)	1074	WP_301675795.1	ABC transporter permease	-
QZH48_RS03050 (QZH48_03050)	-	598479..599048 (-)	570	WP_038599617.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90436.85 Da
• Isoelectric Point: 6.5300

>NTDB_id=856113 QZH48_RS03025 WP_270220371.1 591974..594424(+) (clpC) [Lactococcus lactis subsp. lactis strain CAB701]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQAKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGNEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEIGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=856113 QZH48_RS03025 WP_270220371.1 591974..594424(+) (clpC) [Lactococcus lactis subsp. lactis strain CAB701]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTACGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCACATTTACTGGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCCGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGTTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCATTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATTGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATCTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACCAGCAGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCGGTGAAAATTTCTGTCAAAAATCAACAAGCAAAACG
TCTTGATTTAGAAAAAGAACTAGCCGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAGCTTGACATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTTGCTGACAGTCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAATGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCAGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGCAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCATCAGCGGTGAAATTAATTGCTGAAATAGGTTTTGACCCAGAATATGGTGCACGTCCTC
TACGTAAGGCACTTCAAAAAGAAGTCGAAGACCTTTTAAGTGAACAACTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-453)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.632	100	0.996
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus pneumoniae D39	48.918	100	0.499
clpC	Streptococcus pneumoniae Rx1	48.918	100	0.499
clpC	Streptococcus pneumoniae TIGR4	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	46.87	80.27	0.376
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365