Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   QZH48_RS02540 Genome accession   NZ_CP129879
Coordinates   499562..501808 (+) Length   748 a.a.
NCBI ID   WP_038599374.1    Uniprot ID   A0AAP8JEH2
Organism   Lactococcus lactis subsp. lactis strain CAB701     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 494562..506808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QZH48_RS02520 (QZH48_02520) rpoD 495155..496498 (+) 1344 WP_003130829.1 RNA polymerase sigma factor RpoD -
  QZH48_RS02525 (QZH48_02525) - 496613..497356 (+) 744 WP_010905438.1 MurR/RpiR family transcriptional regulator -
  QZH48_RS02530 (QZH48_02530) - 497521..498888 (+) 1368 WP_038599368.1 MFS transporter -
  QZH48_RS02535 (QZH48_02535) - 499173..499511 (+) 339 WP_038599371.1 hypothetical protein -
  QZH48_RS02540 (QZH48_02540) clpC 499562..501808 (+) 2247 WP_038599374.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  QZH48_RS02545 (QZH48_02545) - 502033..502503 (-) 471 WP_003130820.1 Rrf2 family transcriptional regulator -
  QZH48_RS02550 (QZH48_02550) gap 502676..503689 (+) 1014 WP_301675787.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  QZH48_RS02555 (QZH48_02555) def 503832..504467 (-) 636 WP_003130816.1 peptide deformylase -
  QZH48_RS02560 (QZH48_02560) - 504621..505076 (+) 456 WP_003130814.1 RNA pyrophosphohydrolase -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 83128.87 Da        Isoelectric Point: 4.7623

>NTDB_id=856112 QZH48_RS02540 WP_038599374.1 499562..501808(+) (clpC) [Lactococcus lactis subsp. lactis strain CAB701]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAETKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQEAAETTDEEIPAE

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=856112 QZH48_RS02540 WP_038599374.1 499562..501808(+) (clpC) [Lactococcus lactis subsp. lactis strain CAB701]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTCAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCACAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGTCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAACGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGCCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGCGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATATGTGGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCTTACAGCTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTGCAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGCTTTGGTGCTGCCCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAACTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTTCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATTTAGGTTATAATCCAGCAATGGGTGCAAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAGCAGCAGAAACGACTGATGAAGAAATTCCCGC
TGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(287-386)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(643-713)

AAA domain (Cdc48 subfamily) (AAA_2)

(472-635)

ATPase family associated with various cellular activities (AAA) (AAA)

(149-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

97.727

100

0.977
  clpE Streptococcus mutans UA159

76.026

100

0.767
  clpE Streptococcus pneumoniae Rx1

75.543

98.396

0.743
  clpE Streptococcus pneumoniae D39

75.543

98.396

0.743
  clpE Streptococcus pneumoniae R6

75.543

98.396

0.743
  clpE Streptococcus pneumoniae TIGR4

75.543

98.396

0.743
  clpC Bacillus subtilis subsp. subtilis str. 168

51.672

87.968

0.455
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.635

81.952

0.39
  clpC Streptococcus pneumoniae Rx1

46.635

83.422

0.389
  clpC Streptococcus pneumoniae D39

46.635

83.422

0.389
  clpC Streptococcus pneumoniae TIGR4

46.635

83.422

0.389
  clpC Streptococcus thermophilus LMD-9

46.104

82.353

0.38
  clpC Streptococcus thermophilus LMG 18311

45.942

82.353

0.378
  clpC Streptococcus mutans UA159

45.631

82.62

0.377