Detailed information NTG0856003

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: QZN14_RS06230
• Genome accession: NZ_CP129875
• Coordinates: 1233131..1234357 (-)
• Length: 408 a.a.
• NCBI ID: WP_000918415.1
• Uniprot ID: A0A0H1T4M5
• Organism: Streptococcus agalactiae COH1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1228131..1239357

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZN14_RS06205	-	1229005..1230381 (-)	1377	WP_000427485.1	amino acid permease	-
QZN14_RS06210	-	1230511..1231161 (-)	651	WP_000120093.1	HXXEE domain-containing protein	-
QZN14_RS06215	-	1231319..1231729 (-)	411	WP_001191111.1	HXXEE domain-containing protein	-
QZN14_RS06220	-	1231914..1232462 (+)	549	WP_000140663.1	TetR/AcrR family transcriptional regulator	-
QZN14_RS06225	yihA	1232524..1233120 (-)	597	WP_000796925.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
QZN14_RS06230	clpX	1233131..1234357 (-)	1227	WP_000918415.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
QZN14_RS06235	-	1234575..1235069 (-)	495	WP_000166043.1	dihydrofolate reductase	-
QZN14_RS06240	-	1235149..1235988 (-)	840	WP_000158595.1	thymidylate synthase	-
QZN14_RS06245	-	1236142..1237314 (+)	1173	WP_001874012.1	hydroxymethylglutaryl-CoA synthase	-
QZN14_RS06250	-	1237316..1238599 (+)	1284	WP_000161690.1	hydroxymethylglutaryl-CoA reductase, degradative	-
QZN14_RS06255	-	1238691..1239140 (+)	450	WP_001039192.1	DUF1836 domain-containing protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 44836.25 Da
• Isoelectric Point: 4.4424

>NTDB_id=856003 QZN14_RS06230 WP_000918415.1 1233131..1234357(-) (clpX) [Streptococcus agalactiae COH1]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide

• Length: 1227 bp

>NTDB_id=856003 QZN14_RS06230 WP_000918415.1 1233131..1234357(-) (clpX) [Streptococcus agalactiae COH1]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTGGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTGGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTGTCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAGTTATTGGTTT
TGGACAGACAAGCCGTAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGACCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (109-304)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (311-390)

3D structure

• AlphaFold DB: A0A0H1T4M5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	90.465	100	0.907
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.25	98.039	0.571