Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | KJS82_RS10270 | Genome accession | NZ_AP024511 |
| Coordinates | 2070636..2072264 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus isolate 2007-13 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2033760..2077485 | 2070636..2072264 | within | 0 |
| SCCmec | 2069265..2090605 | 2070636..2072264 | within | 0 |
Gene organization within MGE regions
Location: 2033760..2090605
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KJS82_RS10115 (RVB3_18910) | - | 2033760..2036912 (-) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
| KJS82_RS10120 (RVB3_18920) | - | 2037179..2037781 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| KJS82_RS10125 (RVB3_18930) | - | 2037989..2038285 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| KJS82_RS10130 (RVB3_18940) | - | 2038334..2038537 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| KJS82_RS10135 (RVB3_18950) | - | 2038846..2039832 (+) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| KJS82_RS14825 | - | 2040018..2040232 (+) | 215 | Protein_1979 | universal stress protein | - |
| KJS82_RS10140 (RVB3_18960) | sqr | 2040499..2041692 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| KJS82_RS10145 (RVB3_18970) | cstB | 2041711..2043045 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KJS82_RS10150 (RVB3_18980) | cstA | 2043076..2044140 (-) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| KJS82_RS10155 (RVB3_18990) | cstR | 2044277..2044537 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| KJS82_RS10160 (RVB3_19000) | - | 2044537..2045292 (+) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| KJS82_RS10165 | - | 2045390..2045478 (+) | 89 | Protein_1985 | hypothetical protein | - |
| KJS82_RS10170 (RVB3_19010) | - | 2045783..2046138 (+) | 356 | Protein_1986 | tRNA-dihydrouridine synthase | - |
| KJS82_RS10175 (RVB3_19020) | - | 2046236..2047981 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| KJS82_RS10180 | - | 2048128..2048220 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| KJS82_RS10185 | - | 2048184..2048318 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| KJS82_RS10190 (RVB3_19030) | - | 2048568..2050076 (-) | 1509 | WP_213607902.1 | protein kinase | - |
| KJS82_RS10195 (RVB3_19040) | - | 2050191..2050817 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| KJS82_RS10200 (RVB3_19070) | - | 2051936..2052832 (+) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| KJS82_RS10205 (RVB3_19080) | - | 2052842..2053711 (+) | 870 | WP_000626133.1 | hypothetical protein | - |
| KJS82_RS10210 (RVB3_19090) | - | 2054256..2054813 (-) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| KJS82_RS10215 (RVB3_19100) | - | 2054829..2056850 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| KJS82_RS10220 (RVB3_19110) | kdpA | 2056869..2058545 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| KJS82_RS14830 | kdpF | 2058566..2058646 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| KJS82_RS10230 (RVB3_19120) | - | 2058813..2061482 (+) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| KJS82_RS10235 (RVB3_19130) | - | 2061457..2062152 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| KJS82_RS10240 (RVB3_19140) | - | 2062874..2063800 (+) | 927 | Protein_2000 | YfcC family protein | - |
| KJS82_RS10245 | - | 2064311..2065452 (+) | 1142 | Protein_2001 | IS3-like element ISSau4 family transposase | - |
| KJS82_RS10250 (RVB3_19180) | - | 2065703..2066749 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| KJS82_RS10255 (RVB3_19190) | - | 2066942..2067238 (+) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| KJS82_RS10260 (RVB3_19200) | - | 2067238..2069031 (+) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| KJS82_RS10265 (RVB3_19210) | ccrA | 2069265..2070614 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| KJS82_RS10270 (RVB3_19220) | ccrB | 2070636..2072264 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| KJS82_RS10275 (RVB3_19230) | - | 2072782..2073132 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KJS82_RS10280 (RVB3_19240) | - | 2073219..2073530 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| KJS82_RS10285 (RVB3_19250) | - | 2073548..2074054 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| KJS82_RS10290 (RVB3_19260) | - | 2074075..2074392 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| KJS82_RS10295 (RVB3_19270) | - | 2074511..2075596 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| KJS82_RS10300 (RVB3_19280) | - | 2075593..2077485 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| KJS82_RS10305 (RVB3_19290) | - | 2077492..2077869 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| KJS82_RS10310 (RVB3_19300) | - | 2078020..2078802 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| KJS82_RS10315 (RVB3_19310) | erm(A) | 2078928..2079659 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| KJS82_RS10325 (RVB3_19320) | - | 2080168..2080830 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| KJS82_RS10335 (RVB3_19330) | - | 2081175..2081813 (-) | 639 | Protein_2017 | sulfite exporter TauE/SafE family protein | - |
| KJS82_RS10340 (RVB3_19340) | cstR | 2081813..2082073 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KJS82_RS10345 (RVB3_19350) | - | 2082209..2083273 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KJS82_RS10350 (RVB3_19360) | cstB | 2083306..2084640 (+) | 1335 | Protein_2020 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KJS82_RS10355 (RVB3_19380) | - | 2084754..2085863 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KJS82_RS10360 | psm-mec | 2086218..2086286 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KJS82_RS10365 (RVB3_19390) | mecI | 2086371..2086742 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KJS82_RS10370 (RVB3_19400) | mecR1 | 2086742..2088499 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KJS82_RS10375 (RVB3_19410) | mecA | 2088596..2090605 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=85585 KJS82_RS10270 WP_001186602.1 2070636..2072264(+) (ccrB) [Staphylococcus aureus isolate 2007-13]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=85585 KJS82_RS10270 WP_001186602.1 2070636..2072264(+) (ccrB) [Staphylococcus aureus isolate 2007-13]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |