Detailed information NTG0085552

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KJS82_RS00755
• Genome accession: NZ_AP024511
• Coordinates: 122524..123567 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 2007-13
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 117524..128567

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJS82_RS00725	-	117950..118060 (+)	111	WP_001790257.1	hypothetical protein	-
KJS82_RS00730 (RVB3_01390)	-	118089..118502 (+)	414	WP_001557448.1	hypothetical protein	-
KJS82_RS00735 (RVB3_01400)	-	118933..119919 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
KJS82_RS00740 (RVB3_01410)	map	120450..121208 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KJS82_RS00745 (RVB3_01420)	-	121425..121811 (+)	387	WP_001110179.1	hypothetical protein	-
KJS82_RS00750 (RVB3_01430)	liaF	121826..122527 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
KJS82_RS00755 (RVB3_01440)	vraS	122524..123567 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KJS82_RS00760 (RVB3_01450)	vraR	123557..124186 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
KJS82_RS00765 (RVB3_01460)	-	124299..125516 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
KJS82_RS00770 (RVB3_01470)	-	125794..126069 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
KJS82_RS00775 (RVB3_01480)	-	126076..126540 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KJS82_RS00780 (RVB3_01490)	-	126687..126887 (+)	201	WP_000180460.1	DUF1128 family protein	-
KJS82_RS00785 (RVB3_01500)	-	126890..128146 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=85552 KJS82_RS00755 WP_001017131.1 122524..123567(+) (vraS) [Staphylococcus aureus isolate 2007-13]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=85552 KJS82_RS00755 WP_001017131.1 122524..123567(+) (vraS) [Staphylococcus aureus isolate 2007-13]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1