Detailed information NTG0855156

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V8690_RS24660
• Genome accession: NZ_CP146350
• Coordinates: 5265942..5268467 (+)
• Length: 841 a.a.
• NCBI ID: WP_338782116.1
• Uniprot ID: -
• Organism: Streptomyces sp. DG1A-41
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5260942..5273467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V8690_RS24630 (V8690_24630)	-	5261763..5262440 (+)	678	WP_338785445.1	hypothetical protein	-
V8690_RS24635 (V8690_24635)	-	5262459..5262647 (+)	189	WP_338782107.1	hypothetical protein	-
V8690_RS24640 (V8690_24640)	-	5262817..5263314 (+)	498	WP_338785446.1	BlaI/MecI/CopY family transcriptional regulator	-
V8690_RS24645 (V8690_24645)	-	5263324..5263857 (+)	534	WP_338782109.1	amino-acid N-acetyltransferase	-
V8690_RS24650 (V8690_24650)	-	5264141..5264476 (+)	336	WP_010048839.1	Lsr2 family protein	-
V8690_RS24655 (V8690_24655)	-	5264486..5265511 (-)	1026	WP_338782113.1	SCO3374 family protein	-
V8690_RS24660 (V8690_24660)	clpC	5265942..5268467 (+)	2526	WP_338782116.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V8690_RS24665 (V8690_24665)	-	5268550..5269179 (-)	630	WP_338782117.1	HAD family acid phosphatase	-
V8690_RS24670 (V8690_24670)	-	5269619..5270317 (+)	699	WP_338782120.1	M23 family metallopeptidase	-
V8690_RS24675 (V8690_24675)	-	5270732..5271328 (-)	597	WP_338782122.1	TetR/AcrR family transcriptional regulator	-
V8690_RS24680 (V8690_24680)	-	5271454..5273061 (+)	1608	WP_338782123.1	MDR family MFS transporter	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 92989.21 Da
• Isoelectric Point: 6.0304

>NTDB_id=855156 V8690_RS24660 WP_338782116.1 5265942..5268467(+) (clpC) [Streptomyces sp. DG1A-41]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKETATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQNDAVKALSKAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
ALAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAASGDTKTNYERMKNKVSDELKQHFRPEFLNRVDDVVVFPQLT
QGDILRIVDLMISKVDERLKDRDMGLELAQSAKELLAKKGYDPVMGARPLRRTIQREIEDSLSEKILFGELRPGHIVVVD
TEGEGEAKTFTFRGEEKSALPDVPPIEQAAGGTGPNLSKDV

Nucleotide

• Length: 2526 bp

>NTDB_id=855156 V8690_RS24660 WP_338782116.1 5265942..5268467(+) (clpC) [Streptomyces sp. DG1A-41]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACTGAACACATCCTCCTGGGTCTGATCCACGAGGGTGAAGGTGTCGCCGCCAAGGCCCTTGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTGGGCGCAGATCTGAACCGCG
TGCGGCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGACCGCCACCGCCGGCGGTCCTGCCGAGGGCACG
CCCTCCACGTCCCTGGTCCTCGACCAGTTCGGCCGGAACCTCACCCAGGCCGCTCGCGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACGAAGAACAACCCGGTCCTGATCGGTGAGC
CCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACGCTCAAGGAC
AAGCACCTCTACACGCTGGACCTCGGCGCTCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGTACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCGGTGCGGGTGCCG
CCGAGGGCGCCATCGACGCGGCTTCCATCCTGAAGCCGATGCTGGCCCGCGGTGAGCTCCAGACCATCGGTGCGACGACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCCGAGCCGTC
CCTGCCGCACACGATCGAGATCCTCAAGGGCCTGCGCGACCGTTACGAGGCGCACCACCGCGTCTCCATCACGGACGAGG
CGCTGGTCCAGGCCGCCACCCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGTTCCCGGATGCGTATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGGTGT
CCGCCGCGACAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGAAGGCCGCCTCCCTGCGTGACAAGGAGAAGCAGCTCC
TCGCCGCCAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAACTGATC
GCCGAGGTCCTCGCCACGGCCACGGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGGATGGA
GGACGAGCTCCACAAGCGGGTCATCGGCCAGAACGACGCCGTCAAGGCGCTGTCGAAGGCGATCCGCCGTACGCGTGCCG
GTCTGAAGGACCCGAAGCGTCCCGGTGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCACTCGCCGAGTTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
GTCGCGTCTCTTCGGTTCGCCCCCCGGTTACGTGGGCTATGAAGAGGGCGGCCAGCTGACGGAGAAGGTGCGGCGCAAGC
CGTTCTCGGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTCCAGATCCTGGAGGAC
GGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGCACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCGGCCTCGGGTGACACGAAGACCAACTACGAGCGCATGAAGAACAAGG
TCTCGGACGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGCGTCGACGACGTGGTCGTCTTCCCGCAGCTGACC
CAGGGCGACATCCTGCGGATCGTCGACCTGATGATCAGCAAGGTGGACGAGCGCCTGAAGGACCGGGACATGGGCCTCGA
GCTCGCCCAGTCCGCCAAGGAGCTGCTCGCCAAGAAGGGCTACGACCCCGTCATGGGCGCCCGGCCGCTGCGCCGGACGA
TCCAGCGCGAGATCGAGGACAGCCTGTCGGAGAAGATCCTCTTCGGTGAGCTGCGCCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGCGAGGCCAAGACCTTCACCTTCCGGGGTGAGGAGAAGTCGGCCCTGCCGGACGTCCCGCCGATCGA
GCAGGCGGCCGGTGGCACGGGACCGAACCTGAGCAAGGACGTGTAA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

• AAA lid domain (AAA_lid_9) (349-449)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.358	96.314	0.591
clpC	Streptococcus mutans UA159	44.578	98.692	0.44
clpC	Streptococcus thermophilus LMD-9	43.41	98.335	0.427
clpC	Streptococcus thermophilus LMG 18311	43.237	98.454	0.426
clpC	Streptococcus pneumoniae Rx1	44.583	95.482	0.426
clpC	Streptococcus pneumoniae D39	44.583	95.482	0.426
clpC	Streptococcus pneumoniae TIGR4	44.612	94.887	0.423
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.951	96.314	0.423
clpE	Streptococcus mutans UA159	54.633	74.435	0.407
clpE	Streptococcus pneumoniae TIGR4	53.13	74.078	0.394
clpC	Lactococcus lactis subsp. cremoris KW2	53.387	73.722	0.394
clpE	Streptococcus pneumoniae D39	52.97	74.078	0.392
clpE	Streptococcus pneumoniae R6	52.97	74.078	0.392
clpE	Streptococcus pneumoniae Rx1	52.97	74.078	0.392