Detailed information NTG0855127

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: V8690_RS09735
• Genome accession: NZ_CP146350
• Coordinates: 2070819..2073854 (-)
• Length: 1011 a.a.
• NCBI ID: WP_338777366.1
• Uniprot ID: -
• Organism: Streptomyces sp. DG1A-41
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2065819..2078854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V8690_RS09710 (V8690_09710)	-	2066061..2067008 (+)	948	WP_338777358.1	hypothetical protein	-
V8690_RS09715 (V8690_09715)	-	2067200..2068300 (+)	1101	WP_338777360.1	LacI family DNA-binding transcriptional regulator	-
V8690_RS09720 (V8690_09720)	-	2068297..2069202 (+)	906	WP_338777362.1	carbohydrate kinase	-
V8690_RS09725 (V8690_09725)	-	2069256..2070101 (-)	846	Protein_1930	helix-turn-helix domain-containing protein	-
V8690_RS09730 (V8690_09730)	-	2070271..2070747 (+)	477	WP_338777364.1	YceI family protein	-
V8690_RS09735 (V8690_09735)	uvrA	2070819..2073854 (-)	3036	WP_338777366.1	excinuclease ABC subunit UvrA	Machinery gene
V8690_RS09740 (V8690_09740)	-	2074079..2074768 (+)	690	WP_338777369.1	maleylpyruvate isomerase family mycothiol-dependent enzyme	-
V8690_RS09745 (V8690_09745)	-	2074804..2075460 (+)	657	WP_338777371.1	MBL fold metallo-hydrolase	-
V8690_RS09750 (V8690_09750)	-	2075782..2076645 (+)	864	WP_338777374.1	ABC transporter substrate-binding protein	-
V8690_RS09755 (V8690_09755)	-	2076648..2077523 (+)	876	Protein_1936	amino acid ABC transporter permease	-
V8690_RS09760 (V8690_09760)	-	2077542..2078294 (+)	753	WP_338785302.1	amino acid ABC transporter ATP-binding protein	-
V8690_RS09765 (V8690_09765)	aroQ	2078350..2078823 (-)	474	WP_086599349.1	type II 3-dehydroquinate dehydratase	-

Sequence

Protein

• Length: 1011 a.a.
• Molecular weight: 110873.92 Da
• Isoelectric Point: 7.7233

>NTDB_id=855127 V8690_RS09735 WP_338777366.1 2070819..2073854(-) (uvrA) [Streptomyces sp. DG1A-41]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGETIQLSTPPTLKKQEKHTIEVVVDRLTVKEGAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCSGIGTRMEVDAELIVPDPDKSLDEGAIHPWSHGHTK
DYFGRLIGALADALGFRTDIPFAGLPQRAKKALLHGHKTQVEVRYRNRYGRERRYTTAFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPTCEGTRLKPIVLAVTIMDKSIAEVSAMSISDCADFLRELKLSARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKTAD
WIVDIGPGAGEHGGKVVHSGSLKELLVNAESQTGQYLSGKKAIPLPDIRRPVDPSRQLTVHGARENNLQDIDVSFPLGVF
TAVTGVSGSGKSTLVNDILYTHLARELNGARNVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHIRKLFA
ETTEAKVRGYMPGRFSFNVKGGRCENCAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIADVLNMPIEEA
TEFFEAVPAISRHMKTLKDVGLGYVRLGQSATTLSGGEAQRVKLASELQRRSTGRTVYVLDEPTTGLHFEDISKLLTVLS
GLVDKGNTVIVIEHNLDVIKTADWIVDMGPEGGAGGGLVVAEGTPEEVAAVPASHTGKFLREVLGADRISDASSVKAPRK
TAAKKTVPAQTRATRTATRTVNNTAAGTAAKKTAAKSTKAAAKKTTRTTKG

Nucleotide

• Length: 3036 bp

>NTDB_id=855127 V8690_RS09735 WP_338777366.1 2070819..2073854(-) (uvrA) [Streptomyces sp. DG1A-41]
GTGGCCGACCGTCTCATCGTTCGTGGAGCGCGCGAGCACAATCTCAAGAACGTCTCGCTCGACCTCCCGCGCGACTCGCT
CATCGTCTTCACGGGCCTGTCGGGGTCGGGCAAGTCCTCGCTGGCCTTCGACACCATCTTCGCCGAGGGACAGCGGCGCT
ACGTGGAGTCGCTGTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGACTTCATCGAGGGCCTG
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCCACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTGCGTCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGCCCGATCTCGCGCCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTGGAGCTGCCGGAGGGCAGCCGCTTCCAGGTGCTGTCGCCGCTGGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTCCAGACCAAGGGCTACTCCCGCGCGCGGGTGGACGGCGAGACCATCCAGCT
GTCCACCCCGCCCACGCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACGGTCAAGGAAGGCG
CCAAGCGCCGTCTCACCGACTCCGTCGAGACCGCCCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCGCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAATTCGCCCTTCGGCGCCTGCCCGGACTGCTCCGGCATCGGCACGCGCATGGAGGTCG
ACGCGGAGCTCATCGTCCCGGACCCGGACAAGAGCCTCGACGAGGGTGCCATCCACCCCTGGTCGCACGGCCACACCAAG
GACTACTTCGGCCGCCTGATCGGCGCACTCGCCGACGCCCTGGGCTTCCGTACGGACATCCCCTTCGCGGGCCTCCCGCA
GCGCGCCAAGAAGGCACTGCTCCACGGCCACAAGACCCAGGTCGAGGTCCGCTACCGCAACCGCTACGGGCGCGAGCGCC
GGTACACCACGGCCTTCGAGGGCGCCGTCCCCTTCGTCAAGCGCCGGCACAGCGAGGCCGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCGACCTGTGAGGGCACGCGCCTGAAGCCGATCGTCCTCGCGGTCAC
GATCATGGACAAGTCCATCGCGGAGGTCTCCGCGATGTCGATCAGCGACTGCGCGGACTTCCTGAGGGAGCTGAAGCTCA
GCGCCCGCGACAAGAAGATCGCCGAGCGCGTCCTGAAGGAGGTCAACGAGCGGCTGCGCTTCCTCGTCGACGTCGGCCTG
GACTACCTCTCGCTGAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGTCTGGCCACCCAGATCGG
CTCCGGCCTCGTCGGCGTGCTGTACGTCCTCGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGGCTGATCG
AGACCCTGGTCCGGCTGCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGACCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCCGGTGAGCACGGCGGCAAAGTCGTGCACAGCGGCTCCCTGAAGGAACTGCTCGT
CAACGCCGAGTCGCAGACCGGTCAGTACCTGTCCGGCAAGAAGGCCATCCCGCTGCCCGACATCCGGCGTCCGGTCGACC
CCTCCCGGCAGCTCACGGTGCACGGCGCCCGTGAGAACAACCTCCAGGACATCGACGTCTCGTTCCCGCTGGGCGTGTTC
ACCGCCGTCACCGGCGTGTCCGGCTCCGGCAAGTCGACCCTGGTCAACGACATCCTGTACACGCACCTGGCCCGCGAGCT
GAACGGCGCGAGGAACGTGCCCGGGCGGCACACGCGCGTGGACGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGCACCCCCCGCTCCAACCCGGCCACGTACACCGGCGTCTTCGACCACATCCGCAAGCTGTTCGCC
GAGACCACCGAGGCGAAGGTCCGCGGCTACATGCCCGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAACTG
CGCGGGCGACGGCACCATCAAGATCGAGATGAACTTCCTCCCGGATGTCTACGTCCCGTGCGAGGTCTGCCACGGCGCCC
GGTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGACGTCCTGAACATGCCGATCGAGGAGGCC
ACGGAGTTCTTCGAGGCGGTCCCCGCGATCTCCCGCCACATGAAGACCCTCAAGGACGTCGGCCTCGGCTACGTCCGGCT
CGGCCAGTCCGCGACCACCCTGTCCGGCGGTGAGGCCCAGCGCGTCAAGCTCGCCAGCGAGCTCCAGCGCCGCTCCACCG
GCCGCACGGTCTACGTCCTGGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTGCTGACGGTCCTGTCC
GGACTGGTCGACAAGGGCAACACAGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGACCGCCGACTGGATCGTCGA
CATGGGCCCCGAAGGCGGCGCCGGCGGCGGTCTGGTCGTCGCCGAGGGCACGCCCGAGGAGGTAGCCGCGGTCCCGGCCA
GCCACACCGGCAAGTTCCTGCGCGAGGTCCTCGGCGCCGACCGGATCAGTGACGCGTCCTCCGTCAAGGCACCGCGCAAG
ACGGCCGCGAAGAAGACGGTCCCCGCGCAGACCAGGGCGACCAGGACCGCCACCAGGACGGTCAACAACACCGCGGCCGG
CACCGCGGCCAAGAAGACAGCCGCGAAGTCCACGAAGGCCGCCGCGAAGAAGACGACGCGGACGACGAAGGGCTGA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (294-403)

• UvrA interaction domain (UvrA_inter) (131-238)

• ABC transporter (ABC_tran) (628-864)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.46	93.472	0.537
uvrA	Streptococcus pneumoniae TIGR4	57.46	93.472	0.537
uvrA	Streptococcus pneumoniae D39	57.46	93.472	0.537