Detailed information NTG0854842

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLWG2_RS11715
• Genome accession: NZ_CP129660
• Coordinates: 2267972..2269003 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain Wg2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2262972..2274003

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLWG2_RS11690 (LLWG2_11740)	-	2264175..2264672 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLWG2_RS11695 (LLWG2_11745)	-	2264659..2264868 (-)	210	WP_011677212.1	hypothetical protein	-
LLWG2_RS11700 (LLWG2_11750)	-	2265156..2266046 (+)	891	WP_081146373.1	IS982 family transposase	-
LLWG2_RS11705 (LLWG2_11755)	kwcM	2266153..2267472 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
LLWG2_RS11710 (LLWG2_11760)	-	2267540..2267653 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLWG2_RS11715 (LLWG2_11765)	sepM	2267972..2269003 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLWG2_RS11720 (LLWG2_11770)	coaD	2268987..2269487 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLWG2_RS11725 (LLWG2_11775)	rsmD	2269535..2270074 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLWG2_RS11730 (LLWG2_11780)	-	2270245..2271465 (-)	1221	WP_021164847.1	MFS transporter	-
LLWG2_RS11735 (LLWG2_11785)	lmrP	2271549..2272775 (-)	1227	Protein_2282	multidrug efflux MFS transporter LmrP	-
LLWG2_RS11740 (LLWG2_11790)	-	2272963..2273457 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=854842 LLWG2_RS11715 WP_011677213.1 2267972..2269003(-) (sepM) [Lactococcus cremoris strain Wg2]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=854842 LLWG2_RS11715 WP_011677213.1 2267972..2269003(-) (sepM) [Lactococcus cremoris strain Wg2]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49