Detailed information NTG0854679

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V1460_RS34120
• Genome accession: NZ_CP146101
• Coordinates: 7590702..7593227 (-)
• Length: 841 a.a.
• NCBI ID: WP_338677450.1
• Uniprot ID: -
• Organism: Streptomyces sp. SCSIO 30461
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 7585702..7598227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V1460_RS34105 (V1460_34105)	-	7586764..7588389 (-)	1626	WP_338678333.1	MDR family MFS transporter	-
V1460_RS34110 (V1460_34110)	-	7588580..7589152 (+)	573	WP_338677447.1	helix-turn-helix domain-containing protein	-
V1460_RS34115 (V1460_34115)	-	7589177..7589770 (-)	594	WP_338677448.1	M23 family metallopeptidase	-
V1460_RS34120 (V1460_34120)	clpC	7590702..7593227 (-)	2526	WP_338677450.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V1460_RS34125 (V1460_34125)	-	7593702..7594376 (+)	675	WP_338677451.1	SCO3374 family protein	-
V1460_RS34130 (V1460_34130)	-	7594355..7594690 (-)	336	WP_338677452.1	Lsr2 family protein	-
V1460_RS34135 (V1460_34135)	-	7594858..7595397 (-)	540	WP_338677453.1	amino-acid N-acetyltransferase	-
V1460_RS34140 (V1460_34140)	-	7595407..7595949 (-)	543	WP_338677454.1	BlaI/MecI/CopY family transcriptional regulator	-
V1460_RS34145 (V1460_34145)	-	7596417..7596584 (-)	168	WP_338677455.1	hypothetical protein	-
V1460_RS34150 (V1460_34150)	-	7596598..7597281 (-)	684	WP_338677456.1	hypothetical protein	-
V1460_RS34155 (V1460_34155)	-	7597421..7598218 (-)	798	WP_338677457.1	type III pantothenate kinase	-

Sequence

Protein

• Length: 841 a.a.
• Molecular weight: 93146.46 Da
• Isoelectric Point: 5.9178

>NTDB_id=854679 V1460_RS34120 WP_338677450.1 7590702..7593227(-) (clpC) [Streptomyces sp. SCSIO 30461]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEAATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
TLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVKTGYERMKAKVNEELKQHFRPEFLNRVDDTVVFHQLS
QDDIIQIVDLMIAKVDERLKDRDMGIELSQEAKLLLAKKGYDPVLGARPLRRTIQREIEDLLSEKILFGELRPGHIVVVD
TEGEGEEKKFTFRGEEKSALPDVPPIEQAAGGTGPNLSKDA

Nucleotide

• Length: 2526 bp

>NTDB_id=854679 V1460_RS34120 WP_338677450.1 7590702..7593227(-) (clpC) [Streptomyces sp. SCSIO 30461]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTTATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCTCCGTCCGGGCACATCCCCTTC
ACCCCTCGTGCCAAGAAGGTCCTGGAGCTCTCGCTCCGGGAGGCTCTCCAACTGGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTTGTGAAGCTGGGCGCCGATCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGTTACCAGGGCAAGGAGGCCGCCACCGCGGGCGGACCTGCCGAGGGCACG
CCCTCGACCTCCCTGGTCCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTTTCCCGCCGTACCAAGAACAACCCGGTGCTCATCGGCGAGC
CCGGCGTCGGCAAGACGGCGGTCGTCGAGGGCCTGGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTGGGTGCGCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCCGTACTCGCGGTGACATCATCCTGTTCATCGACGAGCTCCACACCCTGGTGGGTGCGGGTGCCG
CCGAGGGCGCGATCGACGCCGCCAGCATCCTCAAGCCGATGCTGGCCCGCGGTGAGCTCCAGACCATCGGTGCCACCACA
CTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTGGAGCGCCGCTTCCAGCCCATCCAGGTCGCCGAGCCGTC
GCTTCCGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGTTACGAGGCGCACCACCGCGTCTCGATCACGGATGAGG
CCCTGGTCCAGGCCGCCACCCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGATCGAGGATGCGCATCCGCCGGATGACCGCTCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGGGTGT
CCGCCGGGACAAGGAGTCCGCGATCGACTCCCAGGACTTCGAGAAGGCGGCCTCTCTCCGTGACAAGGAGAAGCAGCTGC
TGGCGGCGAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGTGAGCTGATC
GCCGAGGTCCTGGCCACGGCGACCGGTATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCCCGGCTGCTCCGCATGGA
GGACGAGCTCCACAAGCGCGTCATCGGCCAGAAGGACGCCATCAAGGCGCTGTCCCAGGCGATCCGCCGGACCCGCGCGG
GTCTGAAGGACCCGAAGCGCCCCGGTGGGTCGTTCATCTTCGCCGGGCCTTCCGGTGTCGGGAAGACCGAGCTGTCCAAG
ACGCTCGCCGAATTCCTCTTCGGTGACGAGGACGCACTGATCTCCCTCGACATGTCGGAGTTCAGTGAGAAGCACACGGT
TTCGCGGCTCTTCGGCTCCCCGCCCGGATACGTGGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGGTGCGTCGGAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAATTCCCTTCTCCAGATTCTGGAAGAC
GGCCGTCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGACCCG
GGACATCTCCAAGGGCTTCAACCTGGGCTTCGCCGCCCAGGGCGACGTCAAGACCGGTTACGAGCGGATGAAGGCGAAGG
TCAACGAAGAGCTCAAGCAGCACTTCCGGCCGGAGTTCCTCAACCGTGTGGACGACACGGTCGTCTTCCACCAGCTTTCG
CAGGACGACATCATCCAGATCGTCGACCTGATGATCGCCAAGGTGGACGAGCGTCTGAAGGACCGCGACATGGGCATCGA
GCTCAGCCAGGAGGCCAAGCTCCTGCTGGCGAAGAAGGGCTACGACCCGGTCCTCGGCGCCCGCCCGCTGCGCCGGACGA
TCCAGCGCGAGATCGAGGACCTGCTCTCCGAGAAGATCCTCTTCGGTGAGCTGCGTCCCGGTCACATCGTGGTGGTCGAC
ACCGAGGGTGAGGGTGAGGAGAAGAAGTTCACCTTCCGCGGTGAGGAGAAGTCCGCGCTGCCGGACGTCCCGCCGATCGA
GCAGGCGGCAGGCGGCACCGGGCCGAACCTGTCGAAGGACGCGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (349-449)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (719-799)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (209-329)

• AAA domain (Cdc48 subfamily) (AAA_2) (541-712)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	61.347	95.363	0.585
clpC	Streptococcus mutans UA159	44.337	98.692	0.438
clpC	Streptococcus thermophilus LMD-9	42.976	99.881	0.429
clpC	Streptococcus thermophilus LMG 18311	42.806	100	0.428
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.198	96.314	0.426
clpC	Streptococcus pneumoniae D39	44.583	95.482	0.426
clpC	Streptococcus pneumoniae Rx1	44.583	95.482	0.426
clpC	Streptococcus pneumoniae TIGR4	44.612	94.887	0.423
clpE	Streptococcus mutans UA159	53.834	74.435	0.401
clpE	Streptococcus pneumoniae D39	51.73	75.624	0.391
clpE	Streptococcus pneumoniae R6	51.73	75.624	0.391
clpE	Streptococcus pneumoniae Rx1	51.73	75.624	0.391
clpE	Streptococcus pneumoniae TIGR4	52.488	74.078	0.389
clpC	Lactococcus lactis subsp. cremoris KW2	52.258	73.722	0.385