Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   V2W30_RS09800 Genome accession   NZ_CP146022
Coordinates   2093357..2096440 (-) Length   1027 a.a.
NCBI ID   WP_338695402.1    Uniprot ID   A0ACD5A9K3
Organism   Streptomyces sp. Q6     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2088357..2101440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2W30_RS09775 (V2W30_09775) - 2088956..2089933 (+) 978 WP_338695394.1 hypothetical protein -
  V2W30_RS09780 (V2W30_09780) - 2090017..2090448 (-) 432 WP_338695396.1 Rieske (2Fe-2S) protein -
  V2W30_RS09785 (V2W30_09785) - 2090724..2091668 (+) 945 WP_338695398.1 carbohydrate kinase -
  V2W30_RS09790 (V2W30_09790) - 2091729..2092586 (-) 858 WP_338695399.1 helix-turn-helix domain-containing protein -
  V2W30_RS09795 (V2W30_09795) - 2092688..2093275 (+) 588 WP_338695400.1 YceI family protein -
  V2W30_RS09800 (V2W30_09800) uvrA 2093357..2096440 (-) 3084 WP_338695402.1 excinuclease ABC subunit UvrA Machinery gene
  V2W30_RS09805 (V2W30_09805) - 2096740..2097426 (+) 687 WP_338695404.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  V2W30_RS09810 (V2W30_09810) - 2097436..2098092 (+) 657 WP_338695406.1 MBL fold metallo-hydrolase -
  V2W30_RS09815 (V2W30_09815) - 2098207..2099088 (+) 882 WP_338695408.1 ABC transporter substrate-binding protein -
  V2W30_RS09820 (V2W30_09820) - 2099085..2099966 (+) 882 WP_338695410.1 amino acid ABC transporter permease -
  V2W30_RS09825 (V2W30_09825) - 2099963..2100712 (+) 750 WP_338695412.1 amino acid ABC transporter ATP-binding protein -
  V2W30_RS09830 (V2W30_09830) aroQ 2100721..2101194 (-) 474 WP_338695413.1 type II 3-dehydroquinate dehydratase -

Sequence

Protein


Download         Length: 1027 a.a.        Molecular weight: 112302.75 Da        Isoelectric Point: 8.2210

>NTDB_id=854560 V2W30_RS09800 WP_338695402.1 2093357..2096440(-) (uvrA) [Streptomyces sp. Q6]
MTDRLIVRGAREHNLRNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPIARQSPQAIVDKVLSLPEGSRFQVLSPLVRERK
GEFVDLFSDLQTKGYSRARVDGETIQLSEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEDKSLDEGAIHPWSHGHTK
DYFGRLIGALADALGFRTDIPFAGLPQRAKKALIYGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPTCEGTRLKPIVLAVTVMGKSIAEVSAMSISDCADFLGELTLNARDKKIAERVLKEVNERLKFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGPLKELLSNSESMTGQYLSGKKSIPIPDIRRPVDPGRRLTVHGAKENNLRDIDVSFPLGVL
TAVTGVSGSGKSTLVNDILYTHLARELNGARSVPGRHTRVEGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLFA
ETTEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLDVHYKGKSIAEVLDMPIEEA
LDFFEAVPAISRHLRTLNDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVLS
GLVDKGNSVIVIEHNLDVIKTADWIVDMGPEGGNGGGIVVAEGTPEQVASEPASHTGKFLRDVLGADRVSDAAVPAARSR
KTAAKKTVAATKAPAKKTATAKSTGTVTKTAVTKTAAKKTAAKKTTAVKKTAVAKKTAAKKTTGRKS

Nucleotide


Download         Length: 3084 bp        

>NTDB_id=854560 V2W30_RS09800 WP_338695402.1 2093357..2096440(-) (uvrA) [Streptomyces sp. Q6]
GTGACCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAATCTCCGGAATGTCTCGCTCGACCTCCCGCGCGACTCCCT
CATCGTCTTCACCGGTCTGTCCGGCTCCGGCAAGTCCTCGCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGCCGGT
ACGTCGAGTCGCTGTCGTCGTACGCCCGCCAGTTCCTCGGCCAGATGGACAAGCCCGACGTCGACTTCATCGAGGGCCTG
TCGCCGGCCGTCTCGATCGACCAGAAGTCGACGTCGCGCAACCCGCGCTCCACGGTCGGCACCATCACCGAGGTCTACGA
CTACCTCCGTCTGCTGTTCGCGCGCATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGCCCCATCGCGCGCCAGTCGCCGC
AGGCCATCGTCGACAAGGTCCTGTCGCTGCCCGAGGGCAGCCGCTTCCAGGTCCTGTCGCCGCTAGTGCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCAGCGACCTCCAGACCAAGGGCTACTCCCGCGCGCGCGTGGACGGCGAGACGATCCAGCT
GTCCGAGCCGCCGACCCTGAAGAAGCAGGAGAAGCACACGATCGAGGTGGTCGTCGACCGTCTCACCGTGAAGGACTCCG
CCAAGCGCCGCCTGACCGACTCCGTGGAGACCGCGCTCGGTCTCTCCGGCGGCATGGTCGTGCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCGCGTACGACGACCTGTCCTTCGAAGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGACTGCACCGGCATCGGTACGCGCATGGAGGTCG
ACCCCGAGCTGATCGTCCCGGACGAGGACAAGTCGCTCGACGAGGGCGCCATCCACCCGTGGTCGCACGGTCACACCAAG
GACTACTTCGGCCGCCTCATCGGCGCGCTCGCGGACGCCCTCGGCTTCCGCACGGACATCCCGTTCGCCGGACTGCCGCA
GCGCGCCAAGAAGGCGCTCATCTACGGCCACAAGACGCAGATCGAGGTCCGCTACCGCAACCGCTACGGACGTGAGCGGG
TCTACACGACGCCCTTCGAGGGCGCCGTCCCGTTCGTCAAGCGCCGCCACAGCGAGGCCGAGTCGGACGCGAGCCGTGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCACGCGCCTCAAGCCGATCGTCCTCGCCGTCAC
GGTCATGGGGAAGTCCATCGCCGAGGTCTCGGCCATGTCCATCAGTGACTGCGCCGACTTCCTGGGCGAGCTGACGCTGA
ACGCGCGCGACAAGAAGATCGCGGAGCGCGTCCTGAAGGAGGTCAACGAGCGACTCAAGTTCCTCGTCGACGTGGGCCTC
GACTACCTGTCGCTGAACCGGGCCGCGGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTGGCCACCCAGATCGG
CTCCGGCCTCGTCGGCGTCCTGTACGTCCTCGACGAGCCGTCCATCGGCCTGCACCAGCGCGACAACCACCGGCTCATCG
AGACCCTCGTACGGCTGCGTGACATGGGCAACACGCTCATCGTGGTCGAGCACGACGAGGACACGATCAAGGTCGCCGAC
TGGATCGTCGACATCGGCCCCGGCGCGGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGTCCCTTGAAGGAGCTGCTGAG
CAACAGCGAGTCGATGACCGGCCAGTACCTGTCGGGCAAGAAGTCCATCCCGATCCCGGACATCCGCCGCCCGGTGGACC
CCGGACGCCGCCTCACGGTGCACGGGGCCAAGGAGAACAACCTGCGGGACATCGACGTGTCCTTCCCGCTGGGCGTCCTG
ACGGCCGTCACCGGCGTCTCCGGATCCGGCAAGTCGACGCTGGTCAACGACATCCTGTACACGCATCTGGCGCGCGAGCT
GAACGGGGCGCGTTCGGTCCCGGGCCGGCACACGCGCGTGGAGGGCGACGACCTCGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCCATCGGCCGGACCCCCCGGTCGAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTGTTCGCC
GAGACGACCGAGGCGAAGGTCCGCGGCTACCTGCCGGGGCGGTTCTCCTTCAACGTCAAGGGCGGACGCTGCGAGAACTG
CTCGGGCGACGGCACGATCAAGATCGAGATGAACTTCCTGCCGGACGTGTACGTCCCGTGCGAGGTCTGCCACGGCGCGC
GCTACAACCGCGAGACGCTGGACGTCCACTACAAGGGCAAGTCCATCGCCGAGGTCCTGGACATGCCGATCGAGGAGGCG
CTCGACTTCTTCGAGGCGGTCCCGGCGATCTCCCGCCACCTGCGGACGCTCAACGACGTGGGCCTCGGCTACGTCCGCCT
CGGACAGTCCGCACCCACCCTGTCCGGCGGCGAGGCGCAGCGCGTGAAGCTGGCGAGCGAGTTGCAGAAGCGGTCCACGG
GCCGCACTGTCTACGTCCTCGACGAGCCGACCACCGGTCTGCACTTCGAGGACATCAGCAAGCTCATCACCGTGCTGTCG
GGCCTGGTCGACAAGGGCAACTCGGTCATCGTCATCGAGCACAACCTCGACGTCATCAAGACCGCCGACTGGATCGTCGA
CATGGGCCCCGAGGGAGGCAACGGCGGCGGCATCGTCGTCGCCGAGGGCACCCCCGAGCAGGTCGCGTCGGAACCGGCCA
GCCACACCGGCAAGTTCCTGCGTGACGTCCTCGGCGCCGACCGGGTCAGCGACGCGGCGGTGCCCGCGGCGCGTAGCCGG
AAGACCGCGGCGAAGAAGACCGTCGCGGCCACCAAGGCCCCGGCCAAGAAGACGGCCACGGCGAAGTCGACCGGCACGGT
GACGAAGACAGCGGTGACGAAGACCGCGGCGAAGAAGACGGCAGCCAAGAAGACCACGGCCGTCAAGAAGACCGCCGTGG
CCAAGAAGACCGCTGCGAAGAAGACGACCGGCCGGAAGTCCTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

ABC transporter (ABC_tran)

(628-864)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.825

92.016

0.523
  uvrA Streptococcus pneumoniae TIGR4

56.825

92.016

0.523
  uvrA Streptococcus pneumoniae D39

56.825

92.016

0.523