Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   QYT36_RS01995 Genome accession   NZ_CP129562
Coordinates   427769..429118 (+) Length   449 a.a.
NCBI ID   WP_000815640.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 316M     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 427769..445132 427769..429118 within 0
SCCmec 422598..437533 427769..429118 within 0


Gene organization within MGE regions


Location: 422598..445132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYT36_RS01975 (QYT36_01980) - 422598..423752 (-) 1155 WP_000912116.1 ATP-binding protein -
  QYT36_RS01980 (QYT36_01985) - 424207..425253 (+) 1047 WP_001042023.1 hypothetical protein -
  QYT36_RS01985 (QYT36_01990) ssb 425446..425742 (+) 297 WP_000273823.1 cassette chromosome ssDNA-binding protein -
  QYT36_RS01990 (QYT36_01995) cch1 425742..427535 (+) 1794 WP_000079473.1 cassette chromosome replicative helicase -
  QYT36_RS01995 (QYT36_02000) ccrA 427769..429118 (+) 1350 WP_000815640.1 cassette chromosome recombinase CcrA Machinery gene
  QYT36_RS02000 (QYT36_02005) ccrB 429140..430768 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  QYT36_RS02005 (QYT36_02010) - 431290..431640 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  QYT36_RS02010 (QYT36_02015) - 431727..432038 (+) 312 WP_000700851.1 DUF960 family protein -
  QYT36_RS02015 (QYT36_02020) - 432053..432559 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  QYT36_RS02020 (QYT36_02025) - 432608..434218 (+) 1611 Protein_398 IS1182 family transposase -
  QYT36_RS02025 (QYT36_02030) - 434209..434451 (-) 243 Protein_399 type I restriction enzyme endonuclease domain-containing protein -
  QYT36_RS02030 (QYT36_02035) - 434441..435427 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  QYT36_RS02035 (QYT36_02040) mecA 435524..437533 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  QYT36_RS02040 (QYT36_02045) - 437579..438007 (-) 429 WP_000872606.1 MaoC family dehydratase -
  QYT36_RS02045 (QYT36_02050) - 438104..438847 (-) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  QYT36_RS02050 (QYT36_02055) - 439112..439786 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  QYT36_RS02055 (QYT36_02060) aadD1 439988..440749 (+) 762 WP_001014230.1 aminoglycoside O-nucleotidyltransferase ANT(4')-Ia -
  QYT36_RS02060 (QYT36_02065) bleO 440966..441370 (+) 405 WP_001242578.1 bleomycin binding protein -
  QYT36_RS02065 (QYT36_02070) mobV 441877..443139 (+) 1263 WP_000119405.1 MobV family relaxase -
  QYT36_RS02070 (QYT36_02075) - 443384..444367 (+) 984 Protein_408 protein rep -
  QYT36_RS02075 (QYT36_02080) - 444458..445132 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52663.34 Da        Isoelectric Point: 9.9639

>NTDB_id=854453 QYT36_RS01995 WP_000815640.1 427769..429118(+) (ccrA) [Staphylococcus aureus strain 316M]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=854453 QYT36_RS01995 WP_000815640.1 427769..429118(+) (ccrA) [Staphylococcus aureus strain 316M]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGTCGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.55

100

0.976
  ccrA Staphylococcus aureus COL

75.947

100

0.759