Detailed information NTG0854429

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QYT29_RS08560
• Genome accession: NZ_CP129560
• Coordinates: 1764017..1764904 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 727M
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1759017..1769904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYT29_RS08530 (QYT29_08510)	-	1759750..1760511 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
QYT29_RS08535 (QYT29_08515)	-	1760755..1761210 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QYT29_RS08540 (QYT29_08520)	-	1761332..1761433 (+)	102	WP_000731972.1	SE2200 family small protein	-
QYT29_RS08545 (QYT29_08525)	-	1761493..1762917 (-)	1425	WP_000953736.1	alkaline phosphatase	-
QYT29_RS08550 (QYT29_08530)	-	1763115..1763315 (+)	201	WP_000604731.1	hypothetical protein	-
QYT29_RS08555 (QYT29_08535)	braR	1763341..1764006 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QYT29_RS08560 (QYT29_08540)	braS	1764017..1764904 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QYT29_RS08565 (QYT29_08545)	-	1765012..1765767 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
QYT29_RS08570 (QYT29_08550)	-	1765764..1767764 (+)	2001	WP_000776741.1	ABC transporter permease	-
QYT29_RS08575 (QYT29_08555)	-	1768433..1768546 (+)	114	WP_014937089.1	hypothetical protein	-
QYT29_RS08580 (QYT29_08560)	-	1768928..1769188 (+)	261	WP_014937088.1	hypothetical protein	-
QYT29_RS08585 (QYT29_08565)	-	1769198..1769695 (+)	498	WP_001065267.1	glutathione peroxidase	-
QYT29_RS08590 (QYT29_08570)	-	1769803..1769895 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=854429 QYT29_RS08560 WP_000143420.1 1764017..1764904(+) (braS) [Staphylococcus aureus strain 727M]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=854429 QYT29_RS08560 WP_000143420.1 1764017..1764904(+) (braS) [Staphylococcus aureus strain 727M]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993