Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QYT28_RS07820 Genome accession   NZ_CP129556
Coordinates   1556313..1557029 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 137G     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1551313..1562029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYT28_RS07790 (QYT28_07780) - 1551526..1552152 (+) 627 WP_000522388.1 nitroreductase family protein -
  QYT28_RS07795 (QYT28_07785) - 1552513..1553298 (+) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  QYT28_RS07800 hld 1553900..1553980 (-) 81 WP_000046022.1 delta-hemolysin -
  QYT28_RS07805 (QYT28_07795) - 1554270..1554833 (+) 564 WP_001105709.1 accessory gene regulator AgrB -
  QYT28_RS07810 (QYT28_07800) agrD 1554837..1554977 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  QYT28_RS07815 (QYT28_07805) agrC 1555002..1556294 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  QYT28_RS07820 (QYT28_07810) agrA 1556313..1557029 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QYT28_RS07825 (QYT28_07815) - 1557403..1558362 (-) 960 WP_001253292.1 carbohydrate kinase family protein -
  QYT28_RS07830 (QYT28_07820) - 1558359..1559843 (-) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  QYT28_RS07835 (QYT28_07825) - 1559992..1560942 (-) 951 WP_416470801.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=854313 QYT28_RS07820 WP_000688492.1 1556313..1557029(+) (agrA) [Staphylococcus aureus strain 137G]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=854313 QYT28_RS07820 WP_000688492.1 1556313..1557029(+) (agrA) [Staphylococcus aureus strain 137G]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1