Detailed information NTG0854243

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QYT34_RS00680
• Genome accession: NZ_CP129555
• Coordinates: 69594..70637 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 614E
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 64594..75637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYT34_RS00650 (QYT34_00650)	-	65015..66271 (-)	1257	WP_001793983.1	aminopeptidase	-
QYT34_RS00655 (QYT34_00655)	-	66274..66474 (-)	201	WP_000180460.1	DUF1128 family protein	-
QYT34_RS00660 (QYT34_00660)	-	66621..67085 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
QYT34_RS00665 (QYT34_00665)	-	67092..67367 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QYT34_RS00670 (QYT34_00670)	-	67645..68862 (+)	1218	WP_107383206.1	YihY/virulence factor BrkB family protein	-
QYT34_RS00675 (QYT34_00675)	vraR	68975..69604 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QYT34_RS00680 (QYT34_00680)	vraS	69594..70637 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QYT34_RS00685 (QYT34_00685)	liaF	70634..71335 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QYT34_RS00690 (QYT34_00690)	-	71350..71736 (-)	387	WP_001110178.1	hypothetical protein	-
QYT34_RS00695 (QYT34_00695)	map	71953..72711 (-)	759	WP_000636146.1	type I methionyl aminopeptidase	-
QYT34_RS00700 (QYT34_00700)	-	73178..74164 (+)	987	WP_001014423.1	FUSC family protein	-
QYT34_RS00705 (QYT34_00705)	-	74353..74766 (-)	414	WP_001643743.1	hypothetical protein	-
QYT34_RS00710 (QYT34_00710)	-	74795..74905 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=854243 QYT34_RS00680 WP_001017131.1 69594..70637(-) (vraS) [Staphylococcus aureus strain 614E]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=854243 QYT34_RS00680 WP_001017131.1 69594..70637(-) (vraS) [Staphylococcus aureus strain 614E]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1