Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   QYM01_RS02935 Genome accession   NZ_CP129527
Coordinates   599435..601687 (-) Length   750 a.a.
NCBI ID   WP_115250719.1    Uniprot ID   A0A380JR54
Organism   Streptococcus equi subsp. zooepidemicus strain BJ-1     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 594435..606687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYM01_RS02920 (QYM01_02920) ileS 595027..597825 (+) 2799 WP_301900264.1 isoleucine--tRNA ligase -
  QYM01_RS02925 (QYM01_02925) - 598476..598778 (-) 303 WP_115250718.1 DUF1827 family protein -
  QYM01_RS02930 (QYM01_02930) - 598840..599286 (-) 447 WP_037579064.1 NUDIX hydrolase -
  QYM01_RS02935 (QYM01_02935) clpE 599435..601687 (-) 2253 WP_115250719.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  QYM01_RS02940 (QYM01_02940) - 601969..602199 (+) 231 WP_037579069.1 DUF1797 family protein -
  QYM01_RS09960 - 602681..602743 (-) 63 WP_331274784.1 hypothetical protein -
  QYM01_RS09965 - 602995..603750 (-) 756 Protein_552 DUF4573 domain-containing protein -
  QYM01_RS02950 (QYM01_02950) - 604381..605064 (+) 684 WP_301900266.1 amino acid ABC transporter permease -
  QYM01_RS02955 (QYM01_02955) - 605066..605803 (+) 738 WP_012678294.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 750 a.a.        Molecular weight: 83730.17 Da        Isoelectric Point: 5.8379

>NTDB_id=853983 QYM01_RS02935 WP_115250719.1 599435..601687(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGHNGGGHNGYRPNQAQPAQDTNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLQAKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAGA
VGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQS
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYFRDQIAKYKE
MQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLATDLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
EIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMNR
FDGIIEFKPLSKDNLLHIVHLMLDDVNHRLAHNNIHLDVTQKVKEKLVELGYDPKMGARPLRRTIQDHIEDAITDFYLEH
PAEKDLRAVLTSNGHIMIKPVVKSQAKQAD

Nucleotide


Download         Length: 2253 bp        

>NTDB_id=853983 QYM01_RS02935 WP_115250719.1 599435..601687(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain BJ-1]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAATGGAAAGCAAAGACAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATTTTAGGAGGCTACAATGGCAATCAAAAGG
CGCAGCAGCCTTCTCAAAATCCTTTCTTTGATGACTTTTTTGGTGACCTGAACAATTTTAGAGCCTTCGGTCAATTGCCT
AATACACCACCTACCCAATCAGGAGGCCATAATGGCGGAGGTCACAATGGCTACCGTCCCAATCAAGCCCAGCCAGCACA
GGACACTAACAAGGGCTTGCTTGAGGAATTTGGCATTAATATTACTGAAATGGCCAAGCGTGGTGATATTGATCCTGTCA
TCGGACGTGACGATGAGATTATCCGCGTGATCGAGATTCTCAATCGCCGAACAAAAAATAACCCTGTCCTAATCGGTGAG
CCTGGAGTTGGTAAAACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATTGTTGATGGTGATGTGCCACAAAAGCTACAGGC
TAAGCAGGTTATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATTCGCGGCCAATTTGAAGAGCGCATGCAAA
AGCTCATGGAGGAGATCCGTAAACGTCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGGGCA
GTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGCCAC
CACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGCCCT
CGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAGTCA
GCTATCGAAGCAGCCGCCAACCTATCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACTAGA
TGAGGCCGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGATTGAGGCAGAAA
ACCTTAAGGCGCAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAAGAA
ATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATTACCGATAAGACCATCGAAGCAATCGTTGAGCAAAAAAC
CAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTAGCCACCGATCTCAAAAAGCACGTTA
TCGGTCAAGACGATGCTGTTGATAAAATTGCAAAGGCAATCCGTCGCAATCGTGTTGGACTTGGAGCGCCAAATCGTCCT
ATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTTTGG
CTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCATGCTGTGGCTAAGCTTGTCGGTGCCCCTC
CCGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAGCAGGTACGCCGCAACCCTTACTCGCTCATTTTGTTAGAT
GAGATTGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGGCGATTAACCGACGGACAAGG
ACGGACCGTTAGCTTTAAGGATACTATTATCATCATGACATCAAATGCCGGCACCGGCAAAACAGAAGCTTCAGTAGGCT
TTGGCGCTGCTAGAGAAGGGCGGACAAATTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGTCCCGAGTTCATGAACCGT
TTTGATGGCATTATTGAGTTTAAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGTTAA
TCACCGCCTTGCTCACAATAACATTCACCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATGATC
CTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACCACATTGAAGATGCCATTACCGACTTCTACCTTGAGCAC
CCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATCATGATCAAGCCTGTAGTTAAGTCTCAGGCGAA
GCAGGCAGACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(294-391)

ATPase family associated with various cellular activities (AAA) (AAA)

(156-269)

AAA domain (Cdc48 subfamily) (AAA_2)

(479-642)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(650-724)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JR54

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.195

99.067

0.844
  clpE Streptococcus pneumoniae Rx1

82.228

100

0.827
  clpE Streptococcus pneumoniae D39

82.228

100

0.827
  clpE Streptococcus pneumoniae R6

82.228

100

0.827
  clpE Streptococcus pneumoniae TIGR4

82.095

100

0.825
  clpC Lactococcus lactis subsp. cremoris KW2

75.632

100

0.757
  clpC Bacillus subtilis subsp. subtilis str. 168

50.448

89.333

0.451
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.077

84.4

0.397
  clpC Streptococcus pneumoniae Rx1

47.981

82.533

0.396
  clpC Streptococcus pneumoniae D39

47.981

82.533

0.396
  clpC Streptococcus pneumoniae TIGR4

47.819

82.533

0.395
  clpC Streptococcus mutans UA159

47.343

82.8

0.392
  clpC Streptococcus thermophilus LMD-9

46.508

84

0.391
  clpC Streptococcus thermophilus LMG 18311

46.19

84

0.388