Detailed information NTG0853936

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: V6U69_RS02045
• Genome accession: NZ_CP145867
• Coordinates: 383294..385399 (+)
• Length: 701 a.a.
• NCBI ID: WP_410534066.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS10
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 378294..390399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U69_RS02010 (V6U69_02010)	-	378303..378935 (+)	633	WP_002884372.1	nicotinate-nucleotide adenylyltransferase	-
V6U69_RS02015 (V6U69_02015)	yqeK	378932..379522 (+)	591	WP_410534062.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
V6U69_RS02020 (V6U69_02020)	rsfS	379546..379899 (+)	354	WP_014632696.1	ribosome silencing factor	-
V6U69_RS02025 (V6U69_02025)	-	380101..380841 (+)	741	WP_004183284.1	class I SAM-dependent DNA methyltransferase	-
V6U69_RS02030 (V6U69_02030)	-	380847..381938 (+)	1092	WP_410534064.1	nucleotidyltransferase	-
V6U69_RS02035 (V6U69_02035)	-	382080..382334 (+)	255	WP_060971904.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
V6U69_RS02040 (V6U69_02040)	-	382338..382592 (+)	255	WP_021143706.1	Txe/YoeB family addiction module toxin	-
V6U69_RS02045 (V6U69_02045)	clpE	383294..385399 (+)	2106	WP_410534066.1	AAA family ATPase	Regulator
V6U69_RS02050 (V6U69_02050)	-	385833..386609 (+)	777	WP_021143708.1	FxLYD domain-containing protein	-
V6U69_RS02055 (V6U69_02055)	-	386641..386940 (-)	300	WP_060972580.1	hypothetical protein	-
V6U69_RS02060 (V6U69_02060)	-	386937..387356 (-)	420	WP_211181055.1	HIT family protein	-
V6U69_RS02065 (V6U69_02065)	pptA	387421..388152 (+)	732	WP_198463665.1	ABC transporter ATP-binding protein	Regulator
V6U69_RS02070 (V6U69_02070)	pptB	388149..389186 (+)	1038	WP_410534069.1	ABC transporter permease	Regulator
V6U69_RS02075 (V6U69_02075)	ccrZ	389244..390035 (+)	792	WP_002884270.1	cell cycle regulator CcrZ	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77292.20 Da
• Isoelectric Point: 4.7435

>NTDB_id=853936 V6U69_RS02045 WP_410534066.1 383294..385399(+) (clpE) [Streptococcus salivarius strain KSS10]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELVDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2106 bp

>NTDB_id=853936 V6U69_RS02045 WP_410534066.1 383294..385399(+) (clpE) [Streptococcus salivarius strain KSS10]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAATATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGCCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACAAAGAATAACCCAGTCCTTGTAGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAATGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACCAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTGTGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGCTTCAATGCTGTTATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (257-351)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.79	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.002	92.867	0.455
clpE	Streptococcus pneumoniae D39	48.678	91.726	0.447
clpE	Streptococcus pneumoniae R6	48.678	91.726	0.447
clpE	Streptococcus pneumoniae TIGR4	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.678	91.726	0.447
clpC	Bacillus subtilis subsp. subtilis str. 168	45.511	92.154	0.419
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.089	92.867	0.391
clpC	Streptococcus pneumoniae Rx1	43.087	88.73	0.382
clpC	Streptococcus pneumoniae D39	43.087	88.73	0.382
clpC	Streptococcus pneumoniae TIGR4	43.087	88.73	0.382
clpC	Streptococcus thermophilus LMD-9	43.274	88.017	0.381
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Streptococcus mutans UA159	42.332	89.301	0.378