Detailed information NTG0853875

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: V6U68_RS08075
• Genome accession: NZ_CP145866
• Coordinates: 1760823..1762928 (-)
• Length: 701 a.a.
• NCBI ID: WP_410531608.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1755823..1767928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS08035 (V6U68_08015)	pptB	1756168..1757202 (-)	1035	WP_410532096.1	ABC transporter permease	Regulator
V6U68_RS08040 (V6U68_08020)	pptA	1757202..1757933 (-)	732	WP_198463665.1	ABC transporter ATP-binding protein	Regulator
V6U68_RS08045 (V6U68_08025)	-	1757998..1758417 (+)	420	WP_037599159.1	HIT family protein	-
V6U68_RS08050 (V6U68_08030)	-	1758414..1758713 (+)	300	WP_195435440.1	hypothetical protein	-
V6U68_RS08055 (V6U68_08035)	-	1758894..1759061 (-)	168	WP_162837453.1	hypothetical protein	-
V6U68_RS08060 (V6U68_08040)	-	1759079..1759543 (-)	465	WP_410531607.1	hypothetical protein	-
V6U68_RS08065 (V6U68_08045)	-	1759636..1760244 (-)	609	WP_002884297.1	DUF4230 domain-containing protein	-
V6U68_RS08070 (V6U68_08050)	-	1760262..1760387 (-)	126	WP_002884447.1	hypothetical protein	-
V6U68_RS08075 (V6U68_08055)	clpE	1760823..1762928 (-)	2106	WP_410531608.1	AAA family ATPase	Regulator
V6U68_RS08080 (V6U68_08060)	-	1763630..1763884 (-)	255	WP_021143706.1	Txe/YoeB family addiction module toxin	-
V6U68_RS08085 (V6U68_08065)	-	1763888..1764142 (-)	255	WP_060971904.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
V6U68_RS08090 (V6U68_08070)	-	1764284..1765375 (-)	1092	WP_247924774.1	nucleotidyltransferase	-
V6U68_RS08095 (V6U68_08075)	-	1765382..1766122 (-)	741	WP_247924773.1	class I SAM-dependent DNA methyltransferase	-
V6U68_RS08100 (V6U68_08080)	rsfS	1766287..1766637 (-)	351	WP_002891669.1	ribosome silencing factor	-
V6U68_RS08105 (V6U68_08085)	-	1766652..1767152 (-)	501	WP_004183286.1	cysteine hydrolase family protein	-
V6U68_RS08110 (V6U68_08090)	yqeK	1767156..1767749 (-)	594	WP_247924772.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77410.31 Da
• Isoelectric Point: 4.6964

>NTDB_id=853875 V6U68_RS08075 WP_410531608.1 1760823..1762928(-) (clpE) [Streptococcus salivarius strain KSS9]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAENIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEANMEDGILVIKEKDAE

Nucleotide

• Length: 2106 bp

>NTDB_id=853875 V6U68_RS08075 WP_410531608.1 1760823..1762928(-) (clpE) [Streptococcus salivarius strain KSS9]
ATGAACAACAACTTTAACAATATGGACGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCGATTTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGAAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGATCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAA
AACGCTGCCCTAGCCCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTAGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGTACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGTCGTAACCCTTACTCAATCGTCCTTCTTGACGAAATTGAAAAGGCGGATCCTCAAGTCATCA
CCCTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTAATT
ATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGCCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTAATATGGAAGATGGTATCTTGG
TTATCAAAGAAAAAGATGCTGAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• AAA lid domain (AAA_lid_9) (257-351)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.79	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	48.554	93.723	0.455
clpE	Streptococcus pneumoniae R6	48.834	91.726	0.448
clpE	Streptococcus pneumoniae TIGR4	48.834	91.726	0.448
clpE	Streptococcus pneumoniae D39	48.834	91.726	0.448
clpE	Streptococcus pneumoniae Rx1	48.834	91.726	0.448
clpC	Bacillus subtilis subsp. subtilis str. 168	45.356	92.154	0.418
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.089	92.867	0.391
clpC	Streptococcus pneumoniae TIGR4	42.926	88.73	0.381
clpC	Streptococcus pneumoniae Rx1	42.926	88.73	0.381
clpC	Streptococcus pneumoniae D39	42.926	88.73	0.381
clpC	Streptococcus thermophilus LMD-9	42.973	88.302	0.379
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Streptococcus mutans UA159	42.173	89.301	0.377