Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   V6U66_RS08975 Genome accession   NZ_CP145864
Coordinates   1924008..1925231 (-) Length   407 a.a.
NCBI ID   WP_049527520.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1919008..1930231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS08940 (V6U66_08930) - 1919452..1919631 (-) 180 WP_155213961.1 bacteriocin transporter -
  V6U66_RS08945 (V6U66_08935) - 1919660..1920052 (-) 393 WP_003094909.1 hypothetical protein -
  V6U66_RS08950 (V6U66_08940) cipB 1920064..1920303 (-) 240 WP_021152514.1 Blp family class II bacteriocin Regulator
  V6U66_RS08955 (V6U66_08945) - 1920889..1921143 (-) 255 WP_021152515.1 Blp family class II bacteriocin -
  V6U66_RS08960 (V6U66_08950) comE/blpR 1921737..1922477 (+) 741 WP_164332023.1 LytR/AlgR family response regulator transcription factor Regulator
  V6U66_RS08965 (V6U66_08955) - 1922792..1923808 (+) 1017 WP_339313535.1 sensor histidine kinase -
  V6U66_RS08970 (V6U66_08960) - 1923836..1923991 (-) 156 WP_021152520.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  V6U66_RS08975 (V6U66_08965) comB 1924008..1925231 (-) 1224 WP_049527520.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  V6U66_RS08980 (V6U66_08970) comA/nlmT 1925243..1927399 (-) 2157 WP_107372339.1 peptide cleavage/export ABC transporter Regulator
  V6U66_RS08985 (V6U66_08975) - 1927575..1927742 (-) 168 WP_049527517.1 hypothetical protein -
  V6U66_RS08990 (V6U66_08980) - 1927931..1928020 (-) 90 WP_073688908.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  V6U66_RS08995 (V6U66_08985) - 1928160..1928327 (-) 168 WP_049527516.1 hypothetical protein -
  V6U66_RS09000 (V6U66_08990) - 1928343..1928522 (-) 180 WP_004183368.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46000.96 Da        Isoelectric Point: 8.1403

>NTDB_id=853647 V6U66_RS08975 WP_049527520.1 1924008..1925231(-) (comB) [Streptococcus salivarius strain KSS7]
MNSQLFKSTEFYQKRYQNFSTIIIFPLVLLIMFLLSFLLWAKKEVTVEVTGTIEPTSIVATIQSTSDNTIIKNQLRSNKE
VKKGDLLIQYSEKMESSQKESLQKQFDLLSRQETGLKTLEDSINQGTSLFQEENDEFGYQSTFTTFLAQYDSIGQGVNSS
NRESSPQTNLGNETDTASSFEISGFPVQSETLSKTNKNHKMTSKRNSYKSIPLTLDSQYDTDLSSQREVLKAQYLKEAGQ
QLATVQIQKSEVEGKLNQANILLSNTTIKAPEDGIIHLNQSYENLSTVSTGKELAQIYPKIESTKEVFISYYVSSDYILK
LKKGQSVRLTLDEVGNHNMMVLGKIESIDSSAIETEKGNIFRVKAKAKLTAQESRSLKYGFQGRVTSIIDKKSYFAYLKD
KLFNQLN

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=853647 V6U66_RS08975 WP_049527520.1 1924008..1925231(-) (comB) [Streptococcus salivarius strain KSS7]
ATGAATTCTCAATTATTTAAAAGTACGGAATTTTATCAGAAAAGGTATCAAAACTTCTCAACAATTATTATATTTCCATT
AGTCCTTTTGATAATGTTCCTTCTTTCGTTTTTACTTTGGGCAAAAAAAGAGGTAACAGTTGAAGTCACAGGAACGATAG
AGCCTACAAGTATTGTTGCAACAATCCAGTCAACCAGTGACAATACTATTATAAAGAATCAGTTAAGGTCCAATAAAGAA
GTCAAAAAAGGTGATTTATTGATTCAATATTCCGAAAAAATGGAAAGCTCTCAGAAAGAGAGTCTTCAAAAACAATTTGA
TCTTTTAAGTCGTCAGGAGACAGGGCTAAAAACCTTAGAAGATAGTATCAATCAAGGAACTAGCCTTTTTCAGGAAGAAA
ATGATGAATTTGGCTATCAAAGCACATTTACTACTTTCTTAGCCCAATACGATTCTATTGGTCAAGGTGTTAATAGTTCT
AATCGGGAATCAAGTCCCCAAACTAATTTGGGTAATGAAACAGATACTGCTAGTTCTTTTGAAATCAGTGGATTTCCAGT
TCAATCTGAGACATTATCAAAAACAAATAAGAATCATAAGATGACTTCTAAGAGAAATAGTTATAAGTCTATCCCACTTA
CATTGGATAGTCAATACGATACTGATTTATCAAGTCAAAGGGAGGTATTGAAAGCTCAGTATCTTAAGGAAGCTGGACAA
CAATTAGCAACTGTTCAAATACAGAAGTCTGAAGTAGAGGGAAAACTTAACCAAGCGAATATACTATTGTCTAATACAAC
AATAAAGGCACCTGAAGATGGAATAATACATCTTAATCAATCTTATGAAAATCTGTCAACGGTTTCAACAGGTAAGGAAC
TAGCACAGATTTATCCTAAAATAGAGTCTACTAAGGAAGTTTTTATTAGTTATTATGTTAGTTCAGATTATATCCTTAAA
TTAAAAAAAGGTCAGTCAGTTAGACTAACACTTGATGAGGTTGGTAATCATAATATGATGGTTTTAGGTAAGATTGAGAG
CATTGATAGTTCAGCAATTGAAACAGAGAAAGGAAATATCTTTCGAGTTAAAGCAAAGGCAAAGCTAACTGCTCAAGAAT
CTAGAAGTCTTAAATATGGTTTTCAAGGGCGAGTAACTAGTATAATAGATAAAAAAAGCTACTTTGCTTATCTTAAAGAT
AAGTTATTTAATCAGCTTAATTAA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(267-380)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

35.111

100

0.388
  comB Streptococcus pneumoniae Rx1

35.111

100

0.388
  comB Streptococcus pneumoniae D39

35.111

100

0.388
  comB Streptococcus pneumoniae R6

35.111

100

0.388
  comB Streptococcus gordonii str. Challis substr. CH1

33.917

100

0.381
  comB Streptococcus mitis SK321

34.222

100

0.378
  comB Streptococcus mitis NCTC 12261

34

100

0.376