Detailed information NTG0853559

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6U66_RS00300
• Genome accession: NZ_CP145864
• Coordinates: 48764..51322 (+)
• Length: 852 a.a.
• NCBI ID: WP_221739353.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS7
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 43764..56322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U66_RS00280 (V6U66_00280)	purB	43963..45261 (+)	1299	WP_002886310.1	adenylosuccinate lyase	-
V6U66_RS00285 (V6U66_00285)	argS	46138..47829 (-)	1692	WP_002886311.1	arginine--tRNA ligase	-
V6U66_RS00290 (V6U66_00290)	argR	47984..48412 (+)	429	WP_221739359.1	arginine repressor	-
V6U66_RS00295 (V6U66_00295)	-	48412..48771 (+)	360	WP_084871095.1	YlbF family regulator	-
V6U66_RS00300 (V6U66_00300)	hexA	48764..51322 (+)	2559	WP_221739353.1	DNA mismatch repair protein MutS	Machinery gene
V6U66_RS00305 (V6U66_00305)	-	51356..51811 (-)	456	WP_002886315.1	DUF3021 domain-containing protein	-
V6U66_RS00310 (V6U66_00310)	-	51808..52245 (-)	438	WP_181971222.1	LytTR family DNA-binding domain-containing protein	-
V6U66_RS00315 (V6U66_00315)	-	52424..52729 (+)	306	WP_037603797.1	hypothetical protein	-
V6U66_RS00320 (V6U66_00320)	hexB	52781..54718 (+)	1938	WP_037603795.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6U66_RS00325 (V6U66_00325)	-	54849..55070 (+)	222	WP_002886321.1	hypothetical protein	-
V6U66_RS00330 (V6U66_00330)	ruvA	55228..55818 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95493.68 Da
• Isoelectric Point: 4.6799

>NTDB_id=853559 V6U66_RS00300 WP_221739353.1 48764..51322(+) (hexA) [Streptococcus salivarius strain KSS7]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIVERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGASDDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQGKVSPQ
EKPATETHINEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=853559 V6U66_RS00300 WP_221739353.1 48764..51322(+) (hexA) [Streptococcus salivarius strain KSS7]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
CCGTATGGGCGATTTTTACGAATTATTTTACGAGGATGCTGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCCGATAATCCCATTCCTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGG
CTGGAAGTCGTTTTGGTCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCAACCTTCTACTCTCTAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ACTTAGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGCTGGAAAATGCTAG
AACAGGTAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGTACTT
GGATTGACCGTCCTTTAGTGAATCAGGCTGCAATCGTGGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGACCTGACAGAGAGTCTTAAAGGGGTTTACGACATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGC
TAACCCTAAAGATTTGATTCAGCTAGGTCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTAATG
ATGAGGCCTTGTCACGTCTTTTACAAGAATTGGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGCGAGGGGACATCGTGGATCGCAGATATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATAGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCACTTCTTCCGCAAGGCA
ACTCTGAAAAACTCAGAGCGCTTCGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAGATGCTCGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTGGAACGCTATATTGATCGTTTGCAATCTTTGGCTA
AGGCTATTGCGACAGTCGATGTACTTCAGAGTTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACTTATATGCGTC
AGTTGGCCTTGTCAGTCGTTATGGCTCAGATGGGGTCTTACGTACCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCC
ATCTATACGCGTATTGGTGCTTCAGATGACCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCA
GGCCATTAAGCGCGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGGCGTGGGACAGCCACCTATGATGGTATGG
CTTTGGCCCAATCTATTATTGAGTTTATTCATGACAAGGTGGGAGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAATTAGAGGGCGAGACAGTTACCATCCAACCTCAGGGAAAGGTATCGCCTCAA
GAGAAGCCTGCCACTGAAACGCATATTAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTACGTGATTTGGACATTTACAATATGACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.326	100	0.744
mutS	Pseudomonas stutzeri strain ATCC 17587	35.954	100	0.365