NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	V6U65_RS09055	Genome accession	NZ_CP145863
Coordinates	1968665..1969408 (-)	Length	247 a.a.
NCBI ID	WP_002885796.1	Uniprot ID	-
Organism	Streptococcus salivarius strain KSS6
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1963665..1974408

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS09040 (V6U65_09035)	rnpA	1964389..1964724 (-)	336	WP_002891957.1	ribonuclease P protein component	-
V6U65_RS09045 (V6U65_09040)	argH	1964809..1966194 (-)	1386	WP_037601513.1	argininosuccinate lyase	-
V6U65_RS09050 (V6U65_09045)	-	1966521..1967720 (-)	1200	WP_002885646.1	argininosuccinate synthase	-
V6U65_RS09055 (V6U65_09050)	comE/blpR	1968665..1969408 (-)	744	WP_002885796.1	response regulator transcription factor	Regulator
V6U65_RS09060 (V6U65_09055)	-	1969410..1970726 (-)	1317	WP_410534369.1	GHKL domain-containing protein	-
V6U65_RS09065 (V6U65_09060)	-	1970750..1972030 (-)	1281	WP_002885700.1	hypothetical protein	-
V6U65_RS09070 (V6U65_09065)	-	1972052..1972942 (-)	891	WP_002885882.1	hypothetical protein	-
V6U65_RS09075 (V6U65_09070)	-	1973002..1974309 (-)	1308	WP_002885760.1	GHKL domain-containing protein	-

Sequence

Protein

Download Length: 247 a.a. Molecular weight: 28536.83 Da Isoelectric Point: 6.7589

                                >NTDB_id=853539 V6U65_RS09055 WP_002885796.1 1968665..1969408(-) (comE/blpR) [Streptococcus salivarius strain KSS6]

MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD

ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY

FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK

WSEVKEH

Nucleotide

Download Length: 744 bp

                                >NTDB_id=853539 V6U65_RS09055 WP_002885796.1 1968665..1969408(-) (comE/blpR) [Streptococcus salivarius strain KSS6]

ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG

CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAATGAAAAGGGCAACCATC

AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTTGCCTCAGAAATTCGTCAACAAGAT

GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCACTAGA

TTTCATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG

GAGATGTGGATGATGATGAGATTTTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT

TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTGATTACTAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA

TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCCTTTTTAGTTAATTTGGATAACATATCTCGTATTGATA

AGACTCAGTTGATGATTTATTTTGAAAATGGTGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCTCTGCTTAAAAAA

TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	47.5	97.166	0.462
comE/comE2	Streptococcus equinus JB1	42.857	99.19	0.425
comE/comE1	Streptococcus equinus JB1	40.496	97.976	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	37.402	100	0.385
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.402	100	0.385

Detailed information NTG0853539