Detailed information NTG0853526

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: V6U65_RS07995
• Genome accession: NZ_CP145863
• Coordinates: 1754568..1756673 (-)
• Length: 701 a.a.
• NCBI ID: WP_289092916.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS6
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1749568..1761673

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS07965 (V6U65_07960)	trmB	1749875..1750516 (-)	642	WP_003096317.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
V6U65_RS07970 (V6U65_07965)	ccrZ	1750526..1751317 (-)	792	WP_002884270.1	cell cycle regulator CcrZ	-
V6U65_RS07975 (V6U65_07970)	pptB	1751375..1752409 (-)	1035	WP_371748832.1	ABC transporter permease	Regulator
V6U65_RS07980 (V6U65_07975)	pptA	1752409..1753140 (-)	732	WP_014634937.1	ABC transporter ATP-binding protein	Regulator
V6U65_RS07985 (V6U65_07980)	-	1753205..1753624 (+)	420	WP_014634938.1	HIT family protein	-
V6U65_RS07990 (V6U65_07985)	-	1753621..1753920 (+)	300	WP_014634939.1	hypothetical protein	-
V6U65_RS07995 (V6U65_07990)	clpE	1754568..1756673 (-)	2106	WP_289092916.1	AAA family ATPase	Regulator
V6U65_RS08000 (V6U65_07995)	-	1757398..1757652 (-)	255	WP_014634942.1	Txe/YoeB family addiction module toxin	-
V6U65_RS08005 (V6U65_08000)	-	1757656..1757910 (-)	255	WP_013991075.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
V6U65_RS08010 (V6U65_08005)	-	1758072..1761071 (-)	3000	WP_270617512.1	type I restriction endonuclease subunit R	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77348.24 Da
• Isoelectric Point: 4.7224

>NTDB_id=853526 V6U65_RS07995 WP_289092916.1 1754568..1756673(-) (clpE) [Streptococcus salivarius strain KSS6]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAE

Nucleotide

• Length: 2106 bp

>NTDB_id=853526 V6U65_RS07995 WP_289092916.1 1754568..1756673(-) (clpE) [Streptococcus salivarius strain KSS6]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATCCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCAGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTAGGGGACGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCAC
AAGCCATCGTAAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATCGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATCATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCTGGTAGCACTGGCGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCGACAACTCAGGATGAATACCGTAACACTATCTTGAAG
AACGCTGCTCTTGCTCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCATCTGCTGAAGATACCTTCAAGATTCTCCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCAGTAGATTTCTCTGTCC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATGCTAAAGTTCGCATTGAAGAACTTGAAAAGAAAATTGCTAACCACACAGCAGACCTTAAAG
TTACAGCAACTGTCAATGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCCGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATCCGTTTGGATATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCTTACTCAATCGTCCTTCTTGACGAAATTGAAAAGGCAGACCCTCAAGTTATTA
CCCTCCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGACGGTGTCTTGG
TTATCAAAGAAAAAGATGCTGAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• AAA lid domain (AAA_lid_9) (257-351)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.79	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	48.858	93.723	0.458
clpE	Streptococcus pneumoniae D39	48.678	91.726	0.447
clpE	Streptococcus pneumoniae R6	48.678	91.726	0.447
clpE	Streptococcus pneumoniae TIGR4	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.678	91.726	0.447
clpC	Bacillus subtilis subsp. subtilis str. 168	45.511	92.154	0.419
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.089	92.867	0.391
clpC	Streptococcus pneumoniae TIGR4	43.248	88.73	0.384
clpC	Streptococcus pneumoniae Rx1	43.248	88.73	0.384
clpC	Streptococcus pneumoniae D39	43.248	88.73	0.384
clpC	Streptococcus thermophilus LMD-9	43.436	88.017	0.382
clpC	Streptococcus thermophilus LMG 18311	42.973	88.302	0.379
clpC	Streptococcus mutans UA159	42.332	89.301	0.378