Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   V6U64_RS02095 Genome accession   NZ_CP145862
Coordinates   395904..398009 (+) Length   701 a.a.
NCBI ID   WP_049529235.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS4     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 390904..403009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS02060 (V6U64_02060) yqeK 391019..391612 (+) 594 WP_073689584.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  V6U64_RS02065 (V6U64_02065) - 391616..392116 (+) 501 WP_004183286.1 cysteine hydrolase family protein -
  V6U64_RS02070 (V6U64_02070) rsfS 392131..392481 (+) 351 WP_002891669.1 ribosome silencing factor -
  V6U64_RS02075 (V6U64_02075) - 392686..393426 (+) 741 WP_371490794.1 class I SAM-dependent DNA methyltransferase -
  V6U64_RS02080 (V6U64_02080) - 393433..394524 (+) 1092 WP_410536860.1 nucleotidyltransferase -
  V6U64_RS02085 (V6U64_02085) - 394666..394920 (+) 255 WP_410536862.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  V6U64_RS02090 (V6U64_02090) - 394924..395178 (+) 255 WP_014634942.1 Txe/YoeB family addiction module toxin -
  V6U64_RS02095 (V6U64_02095) clpE 395904..398009 (+) 2106 WP_049529235.1 AAA family ATPase Regulator
  V6U64_RS02100 (V6U64_02100) - 398657..398956 (-) 300 WP_002891662.1 hypothetical protein -
  V6U64_RS02105 (V6U64_02105) - 398953..399372 (-) 420 WP_002891660.1 HIT family protein -
  V6U64_RS02110 (V6U64_02110) pptA 399437..400168 (+) 732 WP_037602681.1 ABC transporter ATP-binding protein Regulator
  V6U64_RS02115 (V6U64_02115) pptB 400165..401202 (+) 1038 WP_410536865.1 ABC transporter permease Regulator
  V6U64_RS02120 (V6U64_02120) ccrZ 401260..402051 (+) 792 WP_002884270.1 cell cycle regulator CcrZ -
  V6U64_RS02125 (V6U64_02125) trmB 402061..402702 (+) 642 WP_003096317.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77405.33 Da        Isoelectric Point: 4.7499

>NTDB_id=853364 V6U64_RS02095 WP_049529235.1 395904..398009(+) (clpE) [Streptococcus salivarius strain KSS4]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=853364 V6U64_RS02095 WP_049529235.1 395904..398009(+) (clpE) [Streptococcus salivarius strain KSS4]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTCAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATCCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGGGACGCTGGTGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATTGTTAACGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATCGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGCGATGGCCAAGGCTCTAAAGGTCTTGCTGATATCT
TGAAGCCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCTGCTCTTGCTCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCTTCTGCTGAAGATACCTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTTTTGAAAGCAGCAGTAGATTTCTCTGTCC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAAGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGAAGACCTTAAAG
TCACTGCAACTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAGGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATCATCCGTTTGGATATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTTATCA
CACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACTGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGCCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA lid domain (AAA_lid_9)

(257-351)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.857

99.857

0.468
  clpC Lactococcus lactis subsp. cremoris KW2

49.54

93.01

0.461
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.442

91.583

0.444
  clpC Bacillus subtilis subsp. subtilis str. 168

45.538

92.725

0.422
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.867

0.392
  clpC Streptococcus pneumoniae TIGR4

43.248

88.73

0.384
  clpC Streptococcus pneumoniae Rx1

43.248

88.73

0.384
  clpC Streptococcus pneumoniae D39

43.248

88.73

0.384
  clpC Streptococcus thermophilus LMD-9

42.95

88.017

0.378
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.332

89.301

0.378