Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   V6U63_RS09260 Genome accession   NZ_CP145861
Coordinates   1996049..1997005 (-) Length   318 a.a.
NCBI ID   WP_227071975.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1991049..2002005
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS09230 (V6U63_09215) proC 1991583..1992353 (+) 771 WP_410535062.1 pyrroline-5-carboxylate reductase -
  V6U63_RS09235 (V6U63_09220) - 1992384..1993046 (-) 663 WP_021144681.1 CPBP family intramembrane glutamic endopeptidase -
  V6U63_RS09240 (V6U63_09225) - 1993159..1993605 (-) 447 WP_021144682.1 hypothetical protein -
  V6U63_RS09245 (V6U63_09230) - 1993683..1994339 (-) 657 WP_410535064.1 CPBP family intramembrane glutamic endopeptidase -
  V6U63_RS09250 (V6U63_09235) - 1994351..1994548 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  V6U63_RS09255 (V6U63_09240) - 1994799..1995992 (-) 1194 WP_410535066.1 acetate kinase -
  V6U63_RS09260 (V6U63_09245) comGH 1996049..1997005 (-) 957 WP_227071975.1 class I SAM-dependent methyltransferase Machinery gene
  V6U63_RS09265 (V6U63_09250) comGG 1997050..1997367 (-) 318 WP_227071976.1 competence type IV pilus minor pilin ComGG Machinery gene
  V6U63_RS09270 (V6U63_09255) comGF 1997345..1997782 (-) 438 WP_227071977.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U63_RS09275 (V6U63_09260) comGE 1997769..1997999 (-) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE Machinery gene
  V6U63_RS09280 (V6U63_09265) comGD 1998031..1998459 (-) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U63_RS09285 (V6U63_09270) comGC 1998419..1998745 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U63_RS09290 (V6U63_09275) comGB 1998742..1999842 (-) 1101 WP_144429890.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U63_RS09295 (V6U63_09280) comGA 1999724..2000665 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U63_RS09300 (V6U63_09285) - 2000747..2001109 (-) 363 WP_002887019.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35772.70 Da        Isoelectric Point: 4.4586

>NTDB_id=853319 V6U63_RS09260 WP_227071975.1 1996049..1997005(-) (comGH) [Streptococcus salivarius strain KSS3]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDVLEIGSGTGNLAETLLNNSQKNLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPKVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=853319 V6U63_RS09260 WP_227071975.1 1996049..1997005(-) (comGH) [Streptococcus salivarius strain KSS3]
ATGAATTTTGAAGCAATTGAGACAGCCTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCGCTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCCCTTAATCTAAGCAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAGCTAGGGCAATTG
GAAGCCTTACAAGCCAATCACCAGTTTACACCTGATGCTATTGGATTTATCATTCTTTACCTACTTGAAGGTTTGACCAA
GGACGACCAATTAGATGTTTTGGAGATTGGTTCGGGGACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
ACCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTATATCCAAGAAGATGCTGTTCGACCACATATTCTCAAAGAGAGTGATGTTATTATTAGTGACCTACCTGTTGG
TTACTACCCTAATGATGAAATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCTCATCACCTTCTCA
TGGAGCAATCACTCAAGTACTTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGTCCACAA
AGTGATTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCAGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTTAAAAAACAAACTGAAAATGCTCCTGAGACCTTTGTTTATCCACTTAGTG
ATTTGCAAAACCCAAAGGTCCTCAAAGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

70.159

99.057

0.695
  comGH Streptococcus mutans UA140

70.159

99.057

0.695