Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QYE86_RS10915 Genome accession   NZ_CP129360
Coordinates   2156422..2157138 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CKMM-401M     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2151422..2162138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYE86_RS10885 - 2151641..2152267 (+) 627 WP_000522384.1 nitroreductase family protein -
  QYE86_RS10890 - 2152628..2153413 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  QYE86_RS10895 hld 2154010..2154090 (-) 81 WP_000046022.1 delta-hemolysin -
  QYE86_RS10900 agrB 2154380..2154949 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  QYE86_RS10905 agrD 2154946..2155086 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QYE86_RS10910 agrC 2155111..2156403 (+) 1293 WP_044290665.1 quorum-sensing sensor histidine kinase AgrC -
  QYE86_RS10915 agrA 2156422..2157138 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  QYE86_RS10920 - 2157210..2157319 (+) 110 Protein_2123 hypothetical protein -
  QYE86_RS10925 - 2157507..2158466 (-) 960 WP_001253302.1 carbohydrate kinase -
  QYE86_RS10930 - 2158463..2159947 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  QYE86_RS10935 - 2160096..2161046 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=852759 QYE86_RS10915 WP_000688492.1 2156422..2157138(+) (agrA) [Staphylococcus aureus strain CKMM-401M]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=852759 QYE86_RS10915 WP_000688492.1 2156422..2157138(+) (agrA) [Staphylococcus aureus strain CKMM-401M]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1