Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   V6S27_RS16555 Genome accession   NZ_CP145703
Coordinates   3248333..3251155 (-) Length   940 a.a.
NCBI ID   WP_000357740.1    Uniprot ID   Q3YUS6
Organism   Escherichia coli strain S1-CAM-04-C     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3243333..3256155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6S27_RS16530 (V6S27_16530) tyrB 3244379..3245572 (+) 1194 WP_000486940.1 aromatic amino acid transaminase -
  V6S27_RS16535 (V6S27_16535) - 3245935..3246297 (-) 363 Protein_3048 hypothetical protein -
  V6S27_RS16540 (V6S27_16540) aphA 3246698..3247411 (+) 714 WP_001226928.1 acid phosphatase AphA -
  V6S27_RS16545 (V6S27_16545) yjbQ 3247522..3247938 (+) 417 WP_000270375.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  V6S27_RS16550 (V6S27_16550) yjbR 3247942..3248298 (+) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  V6S27_RS16555 (V6S27_16555) uvrA 3248333..3251155 (-) 2823 WP_000357740.1 excinuclease ABC subunit UvrA Machinery gene
  V6S27_RS16560 (V6S27_16560) ssb 3251410..3251946 (+) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  V6S27_RS16565 (V6S27_16565) yjcB 3252045..3252326 (-) 282 WP_001295689.1 YjcB family protein -
  V6S27_RS16570 (V6S27_16570) pdeC 3252755..3254338 (+) 1584 WP_000019571.1 c-di-GMP phosphodiesterase PdeC -
  V6S27_RS16575 (V6S27_16575) soxS 3254344..3254667 (-) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  V6S27_RS16580 (V6S27_16580) soxR 3254753..3255217 (+) 465 WP_000412424.1 redox-sensitive transcriptional activator SoxR -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103867.54 Da        Isoelectric Point: 6.6066

>NTDB_id=852628 V6S27_RS16555 WP_000357740.1 3248333..3251155(-) (uvrA) [Escherichia coli strain S1-CAM-04-C]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=852628 V6S27_RS16555 WP_000357740.1 3248333..3251155(-) (uvrA) [Escherichia coli strain S1-CAM-04-C]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTCAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAAAAGCCGGACGTCGATCATATTGAGGGGCTTTCT
CCTGCCATCTCGATTGAGCAGAAATCGACGTCTCATAACCCGCGTTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTTTGTTGTTCGCCCGCGTCGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGCC
AGATGGTGGATAACGTGCTGTCGCAGCCGGAAGGTAAACGCCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAAAATCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACACACTATTGAAGTGGTGGTTGATCGCTTCAAGGTGCGTGACGATCTCA
CCCAACGTCTGGCAGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTTGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTATTTTCCGCCAACTTCGCCTGCCCAATTTGCGGCTATAGTATGCGTGAACTGGAACCACGCCT
GTTTTCGTTTAACAACCCGGCGGGTGCCTGCCCGACCTGTGACGGCCTTGGCGTACAGCAATATTTCGATCCTGATCGCG
TGATCCAGAATCCGGAACTGTCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTACTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCATGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGGACGCGTCTGCGTCGGGAAGCGCGCCACGTTTATGTCGAGAATACGCC
GCTACCTGCTATCTCCGACATGAGCATTGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAAACGCTTTCTGGCGGTGAAGCACAGCGTATCCGTCTGGCGAGCCAGATTGGTGCGGGCCTGGTTGG
CGTTATGTACGTGCTGGACGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGACCATGTGATCGACATT
GGCCCGGGCGCAGGTGTACACGGCGGTGAAGTGGTCGCAGAAGGTCCACTGGAAGCGATTATGGCAGTGCCTGAATCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAACGCGTTCCGGCGAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGTAATAACCTGAAAGACGTGACGCTGACGCTGCCAGTCGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGGCTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACGCCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGTTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAAGCCTGTCAGGGCGACGG
TGTGATCAAAGTGGAGATGCACTTCCTGCCGGATATCTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCCGTACCTGCACTGGCGCGTAAGCTGCAAACGTTGATGGATGTTGGCCTGACGTACATTCGCTTGGGGCAGTCCGC
AACCACCCTTTCCGGCGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACACTGT
ATATTCTTGATGAGCCGACCACCGGTTTGCACTTCGCCGATATTCAGCAACTGCTCGACGTGCTGCATAAACTGCGCGAT
CAGGGCAACACCATTGTGGTGATTGAACACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGCGGCGGCGAGATCCTCGTCTCCGGTACGCCAGAAACCGTCGCGGAGTGCGAAGCTTCGCATACGGCAC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YUS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.37

100

0.576
  uvrA Streptococcus pneumoniae TIGR4

57.37

100

0.576
  uvrA Streptococcus pneumoniae D39

57.37

100

0.576