Detailed information NTG0852111

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: QYH60_RS12600
• Genome accession: NZ_CP129292
• Coordinates: 2546027..2548273 (-)
• Length: 748 a.a.
• NCBI ID: WP_058208525.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain KMGR2-43
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2541027..2553273

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYH60_RS12580 (QYH60_12580)	-	2542426..2542887 (-)	462	WP_308858979.1	RNA pyrophosphohydrolase	-
QYH60_RS12585 (QYH60_12585)	def	2543035..2543670 (+)	636	WP_003130816.1	peptide deformylase	-
QYH60_RS12590 (QYH60_12590)	gap	2543813..2544826 (-)	1014	WP_003130818.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
QYH60_RS12595 (QYH60_12595)	-	2544999..2545469 (+)	471	WP_058208345.1	Rrf2 family transcriptional regulator	-
QYH60_RS12600 (QYH60_12600)	clpC	2546027..2548273 (-)	2247	WP_058208525.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QYH60_RS12605 (QYH60_12605)	-	2548324..2548662 (-)	339	WP_021723450.1	hypothetical protein	-
QYH60_RS12610 (QYH60_12610)	-	2548945..2550312 (-)	1368	WP_058208524.1	MFS transporter	-
QYH60_RS12615 (QYH60_12615)	-	2550477..2551220 (-)	744	WP_010905438.1	MurR/RpiR family transcriptional regulator	-
QYH60_RS12620 (QYH60_12620)	rpoD	2551334..2552677 (-)	1344	WP_003130829.1	RNA polymerase sigma factor RpoD	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83171.94 Da
• Isoelectric Point: 4.7892

>NTDB_id=852111 QYH60_RS12600 WP_058208525.1 2546027..2548273(-) (clpC) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MLCQNCNINEATIHLYTSVNGQKKQIDLCQNCYQIMKSGGQEALFGAGNASNGNSDEPFNPFNDIFSALHGQDFNGAAST
QTPPTQTGGRGPRGPQNPRAKQPKGMLEEFGINITESARRGEIDPVIGRDEEIKRVIEILNRRTKNNPVLIGEPGVGKTA
VVEGLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRKRNDVIMFIDEIHEIVGAGSAGDGNMD
AGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQARYEDYHHVKYTDEAIEAAAH
LSNRYIQDRFLPDKAIDLLDESGSKKNLTLKFVDPEDINRRIADAEKKKNEATQAEDFEKAAHFRDQITKLRELQNHEVS
DDEIPVITEKDIEQIVEQKTHIPVGDLKEKEQTQLINLADDLKAHVIGQDEAVDKIAKAIRRSRVGLGKPNRPIGSFLFV
GPTGVGKTELAKQLAKELFGSSESMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHP
DVMHMFLQILEDGRLTDAQGRTVSFKDSLIIMTSNAGTGKVEASVGFGAAREGRTKSVLGQLGDFFSPEFMNRFDGIIEF
SALSKENLLKIVDLMLDEVNEQIGRNDIHLSVTQAAKEKLVDLGYNPAMGARPLRRTIQENIEDSIADFYIEHPEYKELV
ADLIDDKIVISNQAQETAETTDEEVPAE

Nucleotide

• Length: 2247 bp

>NTDB_id=852111 QYH60_RS12600 WP_058208525.1 2546027..2548273(-) (clpC) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGCTTTGTCAAAATTGTAATATTAATGAAGCGACGATTCACCTTTACACAAGTGTAAATGGTCAGAAAAAACAAATTGA
TTTGTGCCAAAACTGTTATCAAATTATGAAATCTGGCGGTCAAGAAGCTTTATTTGGCGCAGGAAATGCCTCAAATGGAA
ATTCTGATGAACCATTTAATCCATTTAATGATATCTTTAGTGCTTTGCACGGTCAAGATTTTAATGGAGCAGCAAGCACT
CAAACTCCACCAACACAAACAGGTGGACGTGGTCCGCGCGGTCCACAAAATCCTCGGGCAAAACAACCTAAAGGAATGTT
AGAAGAATTTGGAATTAACATCACAGAGTCAGCTCGTCGTGGCGAAATTGACCCAGTGATTGGGCGTGATGAAGAAATTA
AACGTGTCATTGAGATTTTAAATCGTAGGACTAAGAATAATCCTGTATTAATTGGTGAACCTGGTGTTGGTAAAACAGCA
GTTGTTGAAGGTTTAGCGCAAAAAATTGTGGACGGAGATGTGCCGCAAAAACTACAAAATAAAGAAGTGATTCGTCTTGA
TGTTGTTTCTCTTGTTCAAGGAACAGGAATTCGTGGACAATTTGAAGAACGGATGCAAAAATTAATGGATGAAATCAGAA
AACGTAATGATGTGATTATGTTTATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCTGCCGGTGATGGCAATATGGAT
GCAGGAAATATCCTAAAACCTGCGCTTGCGCGTGGTGAGCTTCAATTGGTCGGAGCAACAACGCTCAATGAATATCGCAT
CATTGAAAAAGATGCTGCGCTTGAACGTCGGATGCAACCAGTTAAAGTCGATGAACCATCAGTTGATGAAACAATTACTA
TTTTGCGAGGCATTCAAGCACGTTATGAAGATTATCATCACGTGAAATACACTGATGAGGCTATTGAAGCAGCCGCTCAT
TTGTCAAATCGTTACATTCAAGACCGTTTCTTACCAGATAAAGCCATTGACCTTTTGGATGAGTCTGGTTCTAAGAAAAA
TCTAACCTTGAAATTTGTTGATCCTGAAGATATTAATCGTCGGATTGCGGATGCAGAAAAGAAGAAAAATGAAGCAACAC
AGGCTGAAGATTTTGAAAAAGCCGCTCATTTCCGTGACCAAATCACTAAACTTCGTGAATTACAAAATCATGAAGTTTCA
GATGATGAAATTCCTGTCATCACTGAAAAAGATATTGAACAAATTGTTGAGCAAAAAACACATATTCCAGTTGGTGATTT
GAAAGAAAAAGAACAAACCCAATTGATTAATTTGGCTGATGATTTGAAAGCACATGTGATTGGTCAGGATGAAGCAGTGG
ATAAGATTGCTAAAGCTATCCGTCGTTCTCGTGTGGGACTTGGTAAACCTAATCGTCCAATTGGTTCTTTCCTTTTCGTT
GGTCCAACAGGTGTTGGTAAAACAGAACTTGCTAAACAATTGGCTAAAGAATTATTTGGCTCAAGCGAAAGTATGATTCG
TTTTGACATGTCGGAATACATGGAAAAACATTCGGTGGCCAAATTGATTGGAGCCCCTCCAGGATACGTAGGTTATGAAG
AAGCTGGTCAATTGACTGAACGTGTTCGTCGTAATCCCTACAGTTTGATTTTATTAGATGAAATCGAAAAAGCACATCCA
GATGTGATGCACATGTTCTTACAAATTCTTGAAGATGGACGTCTGACAGACGCACAAGGACGGACAGTATCCTTTAAAGA
TAGTTTGATTATTATGACTTCTAATGCCGGAACTGGTAAAGTTGAAGCCTCTGTCGGATTTGGTGCTGCTCGTGAGGGAC
GAACTAAATCAGTGCTTGGTCAGCTTGGCGATTTCTTTAGCCCTGAATTCATGAACCGTTTTGACGGAATTATTGAATTC
TCTGCTTTGAGCAAAGAAAATCTCCTTAAAATTGTTGATTTGATGCTTGATGAAGTCAACGAACAAATTGGACGTAATGA
TATTCATCTTAGTGTCACTCAAGCAGCAAAAGAAAAATTAGTTGATTTAGGTTACAATCCAGCAATGGGTGCTAGACCAC
TTCGTAGAACAATTCAAGAAAATATCGAAGATTCAATTGCTGACTTCTATATTGAACACCCTGAATACAAAGAATTGGTT
GCTGATTTGATTGATGATAAAATTGTTATCTCTAATCAAGCTCAAGAAACAGCAGAAACGACTGATGAAGAAGTTCCTGC
TGAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (287-386)

• ATPase family associated with various cellular activities (AAA) (AAA) (149-268)

• AAA domain (Cdc48 subfamily) (AAA_2) (472-635)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (643-713)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	97.995	100	0.98
clpE	Streptococcus mutans UA159	76.026	100	0.767
clpE	Streptococcus pneumoniae Rx1	75.543	98.396	0.743
clpE	Streptococcus pneumoniae D39	75.543	98.396	0.743
clpE	Streptococcus pneumoniae R6	75.543	98.396	0.743
clpE	Streptococcus pneumoniae TIGR4	75.543	98.396	0.743
clpC	Bacillus subtilis subsp. subtilis str. 168	51.824	87.968	0.456
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.635	81.952	0.39
clpC	Streptococcus pneumoniae Rx1	46.795	83.422	0.39
clpC	Streptococcus pneumoniae D39	46.795	83.422	0.39
clpC	Streptococcus pneumoniae TIGR4	46.795	83.422	0.39
clpC	Streptococcus thermophilus LMD-9	45.942	82.353	0.378
clpC	Streptococcus thermophilus LMG 18311	45.779	82.353	0.377
clpC	Streptococcus mutans UA159	45.469	82.62	0.376