Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   QYH60_RS03380 Genome accession   NZ_CP129292
Coordinates   663162..664190 (+) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis subsp. lactis strain KMGR2-43     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 658162..669190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYH60_RS03355 (QYH60_03355) - 658708..659202 (-) 495 WP_301401287.1 RNA polymerase sigma factor -
  QYH60_RS03360 (QYH60_03360) lmrP 659390..660616 (+) 1227 WP_301401288.1 multidrug efflux MFS transporter LmrP -
  QYH60_RS03365 (QYH60_03365) - 660700..661920 (+) 1221 WP_012898647.1 MFS transporter -
  QYH60_RS03370 (QYH60_03370) rsmD 662091..662630 (+) 540 WP_050558566.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  QYH60_RS03375 (QYH60_03375) coaD 662678..663175 (+) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  QYH60_RS03380 (QYH60_03380) sepM 663162..664190 (+) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  QYH60_RS03385 (QYH60_03385) - 664512..664625 (+) 114 WP_301401289.1 KxxxW-cyclized peptide pheromone -
  QYH60_RS03390 (QYH60_03390) kwcM 664693..666012 (+) 1320 WP_058207975.1 KxxxW cyclic peptide radical SAM maturase -
  QYH60_RS03395 (QYH60_03395) - 666009..667148 (+) 1140 WP_012898644.1 MFS transporter -
  QYH60_RS03400 (QYH60_03400) - 667259..668116 (+) 858 WP_058203259.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=852076 QYH60_RS03380 WP_003132657.1 663162..664190(+) (sepM) [Lactococcus lactis subsp. lactis strain KMGR2-43]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=852076 QYH60_RS03380 WP_003132657.1 663162..664190(+) (sepM) [Lactococcus lactis subsp. lactis strain KMGR2-43]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AAGTCTTCTTAGTGCCTGATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491