Detailed information NTG0851419

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLD17_RS12540
• Genome accession: NZ_CP129182
• Coordinates: 2299218..2300249 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain D.1.7
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2294218..2305249

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLD17_RS12515 (LLD17_12560)	-	2295421..2295918 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLD17_RS12520 (LLD17_12565)	-	2295905..2296114 (-)	210	WP_011677212.1	hypothetical protein	-
LLD17_RS12525 (LLD17_12570)	-	2296402..2297292 (+)	891	WP_081196975.1	IS982-like element IS982B family transposase	-
LLD17_RS12530 (LLD17_12575)	kwcM	2297399..2298718 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
LLD17_RS12535 (LLD17_12580)	-	2298786..2298899 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLD17_RS12540 (LLD17_12585)	sepM	2299218..2300249 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLD17_RS12545 (LLD17_12590)	coaD	2300233..2300733 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLD17_RS12550 (LLD17_12595)	rsmD	2300781..2301320 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLD17_RS12555 (LLD17_12600)	-	2301491..2302711 (-)	1221	WP_011677216.1	MFS transporter	-
LLD17_RS12560 (LLD17_12605)	lmrP	2302795..2304020 (-)	1226	Protein_2303	multidrug efflux MFS transporter LmrP	-
LLD17_RS12565 (LLD17_12610)	-	2304208..2304702 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=851419 LLD17_RS12540 WP_011677213.1 2299218..2300249(-) (sepM) [Lactococcus cremoris strain D.1.7]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=851419 LLD17_RS12540 WP_011677213.1 2299218..2300249(-) (sepM) [Lactococcus cremoris strain D.1.7]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49