Detailed information NTG0851319

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLNCDO702_RS11855
• Genome accession: NZ_CP129159
• Coordinates: 2356725..2357753 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis subsp. lactis strain NCDO702
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2351725..2362753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLNCDO702_RS11830 (LLNCDO702_11820)	-	2352011..2352508 (-)	498	WP_003132662.1	nitroreductase family protein	-
LLNCDO702_RS11835 (LLNCDO702_11825)	-	2352495..2352704 (-)	210	WP_003132661.1	hypothetical protein	-
LLNCDO702_RS11840 (LLNCDO702_11830)	-	2352701..2353528 (-)	828	WP_014570829.1	radical SAM protein	-
LLNCDO702_RS11845 (LLNCDO702_11835)	-	2353521..2355644 (-)	2124	WP_003132659.1	radical SAM protein	-
LLNCDO702_RS11850 (LLNCDO702_11840)	-	2355747..2356604 (-)	858	WP_003132658.1	Rgg/GadR/MutR family transcriptional regulator	-
LLNCDO702_RS11855 (LLNCDO702_11845)	sepM	2356725..2357753 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LLNCDO702_RS11860 (LLNCDO702_11850)	coaD	2357740..2358237 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LLNCDO702_RS11865 (LLNCDO702_11855)	rsmD	2358285..2358824 (-)	540	WP_003132655.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLNCDO702_RS11870 (LLNCDO702_11860)	-	2358995..2360215 (-)	1221	WP_081144368.1	MFS transporter	-
LLNCDO702_RS11875 (LLNCDO702_11865)	lmrP	2360299..2361523 (-)	1225	Protein_2310	multidrug efflux MFS transporter LmrP	-
LLNCDO702_RS11880 (LLNCDO702_11870)	-	2361711..2362205 (+)	495	WP_012898649.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=851319 LLNCDO702_RS11855 WP_003132657.1 2356725..2357753(-) (sepM) [Lactococcus lactis subsp. lactis strain NCDO702]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=851319 LLNCDO702_RS11855 WP_003132657.1 2356725..2357753(-) (sepM) [Lactococcus lactis subsp. lactis strain NCDO702]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTGGTGCCTGACTCAGGCACCAAAAAAGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491