Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QU610_RS02565 Genome accession   NZ_CP129105
Coordinates   530322..532106 (-) Length   594 a.a.
NCBI ID   WP_137296737.1    Uniprot ID   -
Organism   Helicobacter pylori strain HP45k     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 525322..537106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QU610_RS02535 (QU610_02535) - 525726..525974 (+) 249 WP_000790557.1 RNA-binding protein -
  QU610_RS02540 (QU610_02540) - 526176..526997 (-) 822 WP_137296733.1 glycosyltransferase family 25 protein -
  QU610_RS02545 (QU610_02545) trxB 527353..528288 (-) 936 WP_137296734.1 thioredoxin-disulfide reductase -
  QU610_RS02550 (QU610_02550) trxA 528293..528613 (-) 321 WP_000020199.1 thioredoxin -
  QU610_RS02555 (QU610_02555) - 528702..529046 (-) 345 WP_137296735.1 YraN family protein -
  QU610_RS02560 (QU610_02560) - 529046..530311 (-) 1266 WP_137296736.1 homoserine dehydrogenase -
  QU610_RS02565 (QU610_02565) uvrC 530322..532106 (-) 1785 WP_137296737.1 excinuclease ABC subunit UvrC Machinery gene
  QU610_RS02570 (QU610_02570) - 532107..532568 (-) 462 WP_137296738.1 hypothetical protein -
  QU610_RS02575 (QU610_02575) - 532560..532739 (+) 180 WP_000468793.1 hypothetical protein -
  QU610_RS02580 (QU610_02580) - 532751..533392 (-) 642 WP_137296739.1 ATP-binding cassette domain-containing protein -
  QU610_RS02585 (QU610_02585) - 533394..535055 (-) 1662 WP_137296740.1 ABC transporter permease/substrate-binding protein -
  QU610_RS02590 (QU610_02590) - 535123..535560 (-) 438 WP_001039460.1 hypothetical protein -
  QU610_RS02595 (QU610_02595) motB 535566..536339 (-) 774 WP_137296741.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68833.19 Da        Isoelectric Point: 9.7789

>NTDB_id=850869 QU610_RS02565 WP_137296737.1 530322..532106(-) (uvrC) [Helicobacter pylori strain HP45k]
MADLLSSLKNLPNNSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIKRCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGTSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALIIPKKGDKLALIEIAMKNAQEIFSQERTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=850869 QU610_RS02565 WP_137296737.1 530322..532106(-) (uvrC) [Helicobacter pylori strain HP45k]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAATAGTGGCGTGTATCAATACTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCAAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATTATCGCGCTAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAAAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAGGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCACAAGCAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTATCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAGAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAATGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTTCAAAAAAACTCTTATCGGCG
CTACCATTTGAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGAGCTTTAGATTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGTGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAAGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.98

100

0.98