Detailed information NTG0850855

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLUC320_RS11275
• Genome accession: NZ_CP129095
• Coordinates: 2203061..2204092 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain UC320
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2198061..2209092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC320_RS11250 (LLUC320_11305)	-	2199264..2199761 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLUC320_RS11255 (LLUC320_11310)	-	2199748..2199957 (-)	210	WP_011677212.1	hypothetical protein	-
LLUC320_RS11260 (LLUC320_11315)	-	2200245..2201135 (+)	891	WP_081196975.1	IS982-like element IS982B family transposase	-
LLUC320_RS11265 (LLUC320_11320)	kwcM	2201242..2202561 (-)	1320	WP_014573366.1	KxxxW cyclic peptide radical SAM maturase	-
LLUC320_RS11270 (LLUC320_11325)	-	2202629..2202742 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLUC320_RS11275 (LLUC320_11330)	sepM	2203061..2204092 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLUC320_RS11280 (LLUC320_11335)	coaD	2204076..2204576 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLUC320_RS11285 (LLUC320_11340)	rsmD	2204624..2205163 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLUC320_RS11290 (LLUC320_11345)	-	2205334..2206554 (-)	1221	WP_011677216.1	MFS transporter	-
LLUC320_RS11295 (LLUC320_11350)	lmrP	2206638..2207863 (-)	1226	Protein_2194	multidrug efflux MFS transporter LmrP	-
LLUC320_RS11300 (LLUC320_11355)	-	2208051..2208545 (+)	495	WP_021164846.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=850855 LLUC320_RS11275 WP_011677213.1 2203061..2204092(-) (sepM) [Lactococcus cremoris strain UC320]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=850855 LLUC320_RS11275 WP_011677213.1 2203061..2204092(-) (sepM) [Lactococcus cremoris strain UC320]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTATGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49