Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   LBA42_RS05950 Genome accession   NZ_CP145437
Coordinates   1192524..1195355 (-) Length   943 a.a.
NCBI ID   WP_001152844.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1187524..1200355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS05915 (LBA42_05915) - 1187703..1188953 (-) 1251 WP_000464338.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  LBA42_RS05920 (LBA42_05920) - 1189208..1189513 (-) 306 WP_000017620.1 DUF1292 domain-containing protein -
  LBA42_RS05925 (LBA42_05925) ruvX 1189529..1189948 (-) 420 WP_001808830.1 Holliday junction resolvase RuvX -
  LBA42_RS05930 (LBA42_05930) - 1189952..1190218 (-) 267 WP_000507059.1 IreB family regulatory phosphoprotein -
  LBA42_RS05935 (LBA42_05935) - 1190305..1190874 (-) 570 WP_000725152.1 SP0191 family lipoprotein -
  LBA42_RS05940 (LBA42_05940) spx 1190940..1191338 (-) 399 WP_000591165.1 transcriptional regulator Spx -
  LBA42_RS05945 (LBA42_05945) - 1191470..1192531 (-) 1062 WP_001042855.1 Xaa-Pro peptidase family protein -
  LBA42_RS05950 (LBA42_05950) uvrA 1192524..1195355 (-) 2832 WP_001152844.1 excinuclease ABC subunit UvrA Machinery gene
  LBA42_RS05955 (LBA42_05955) - 1195487..1196431 (+) 945 WP_000815629.1 magnesium transporter CorA family protein -
  LBA42_RS05960 (LBA42_05960) - 1196443..1197126 (+) 684 WP_000078022.1 DUF1129 domain-containing protein -
  LBA42_RS05965 (LBA42_05965) - 1197381..1198412 (+) 1032 WP_000255092.1 S66 peptidase family protein -
  LBA42_RS05970 (LBA42_05970) - 1198567..1199244 (-) 678 WP_000987429.1 type II CAAX endopeptidase family protein -
  LBA42_RS05975 (LBA42_05975) - 1199241..1199804 (-) 564 WP_000166605.1 DNA-3-methyladenine glycosylase I -

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104159.27 Da        Isoelectric Point: 6.3544

>NTDB_id=850736 LBA42_RS05950 WP_001152844.1 1192524..1195355(-) (uvrA) [Streptococcus pneumoniae strain HAC 39-1996]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKADVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYM
NELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=850736 LBA42_RS05950 WP_001152844.1 1192524..1195355(-) (uvrA) [Streptococcus pneumoniae strain HAC 39-1996]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGCT
GGTTGTCGTGACAGGTTTGTCAGGTTCAGGGAAATCCAGTCTGGCCTTTGATACCCTCTATGCGGAGGGACAACGTCGCT
ATGTAGAGAGTTTGTCAGCCTATGCTCGTCAATTCTTAGGAAATATGGAGAAGGCGGATGTGGATGCCATTGATGGTCTC
AGTCCAGCTATTTCTATCGACCAGAAAACGACTAGCAAAAACCCTCGCTCGACGGTGGGAACAACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGG
AGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCCCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCA
TTCGTAGTCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATTGCAGAAGGTTATGTCATTATCGACACCATGGACGAC
TCTGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTCTC
TTTCAATGCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCCAGCAAAACCTTACGTGAGGGAGCGTTAGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCT
CTATGGGTCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGACATTCCGTTTG
AGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGG
GCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATG
AAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCT
ATCAGGCGTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGAGACAATGACCGCCTGATTGCCAGTCTGA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAA
GTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTA
TTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTTAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTC
AGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCG
GACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTG
AAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGGCTAGGCTATGTGACCTTGGGACAGCCAGC
TACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACAGGAAAATCTTTCT
ACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
GATGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAATGAAGCCAGCTATACAGGAC
ACTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-238)

ABC transporter (ABC_tran)

(624-860)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

99.894

100

0.999
  uvrA Streptococcus pneumoniae TIGR4

99.894

100

0.999
  uvrA Streptococcus pneumoniae D39

99.894

100

0.999