Detailed information NTG0850359

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V5G10_RS05185
• Genome accession: NZ_CP145086
• Coordinates: 1006385..1008958 (+)
• Length: 857 a.a.
• NCBI ID: WP_003696969.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_C_2024
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1001385..1013958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G10_RS05165 (V5G10_05165)	ppx	1002110..1003618 (+)	1509	WP_003693399.1	exopolyphosphatase	-
V5G10_RS05170 (V5G10_05170)	-	1003828..1004172 (-)	345	WP_010358382.1	hypothetical protein	-
V5G10_RS05175 (V5G10_05175)	-	1004489..1005034 (-)	546	WP_003690987.1	hypothetical protein	-
V5G10_RS05180 (V5G10_05180)	trpS	1005115..1006125 (-)	1011	WP_003690986.1	tryptophan--tRNA ligase	-
V5G10_RS05185 (V5G10_05185)	clpC	1006385..1008958 (+)	2574	WP_003696969.1	ATP-dependent chaperone ClpB	Regulator
V5G10_RS05190 (V5G10_05190)	-	1009030..1010244 (-)	1215	WP_003695054.1	pyridoxal phosphate-dependent aminotransferase	-
V5G10_RS05195 (V5G10_05195)	-	1010333..1010542 (-)	210	WP_003688192.1	4-oxalocrotonate tautomerase family protein	-
V5G10_RS05200 (V5G10_05200)	-	1010734..1011540 (+)	807	WP_003704212.1	DUF4198 domain-containing protein	-
V5G10_RS05205 (V5G10_05205)	-	1011600..1012819 (-)	1220	Protein_1020	Glu/Leu/Phe/Val dehydrogenase	-
V5G10_RS05210 (V5G10_05210)	-	1013214..1013924 (+)	711	WP_003690977.1	phosphoglycolate phosphatase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 94807.11 Da
• Isoelectric Point: 5.1970

>NTDB_id=850359 V5G10_RS05185 WP_003696969.1 1006385..1008958(+) (clpC) [Neisseria gonorrhoeae strain WHO_C_2024]
MRYDKLTAKFQQALAEAQSLALVADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVATAELSDRYITDRFLPDKAIDLIDEAASR
IKMELDSKPEQMDKLDRRIIQLKMEKMHVAKESDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAASSSTADIKKQMD
DIKVKIEQAKRQGDFARASELEYGELPKLGAQLQAAESNPDGKKQNKLFRTEVGADEVAEIVSRMTGIPVSKMMEGERDK
LLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSEYM
EKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSDAA
LDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2574 bp

>NTDB_id=850359 V5G10_RS05185 WP_003696969.1 1006385..1008958(+) (clpC) [Neisseria gonorrhoeae strain WHO_C_2024]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGTTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATCAATGCCGCGATCGATGCGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAGAAAGACGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTCGGCGAACCCAGCGTGGAAGACACCAT
CGCCATCCTGCGCGGCTTGCAGGAACGCTATGAAATCCACCACGGTATCGACATTACCGACCCCGCCATTGTTGCCACAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTTTTGCCCGACAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGC
ATCAAAATGGAGCTGGACAGCAAACCCGAACAGATGGACAAACTCGACCGCCGCATCATCCAGCTCAAAATGGAAAAAAT
GCACGTTGCCAAAGAAAGCGATGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAAGAAATCGACGGCCTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCCGCGTCTTCCAGCACTGCCGACATCAAGAAACAAATGGAC
GACATCAAAGTCAAAATCGAACAAGCCAAACGTCAAGGCGACTTCGCCCGCGCGTCCGAACTCGAATACGGCGAGTTGCC
GAAATTGGGCGCACAGTTGCAGGCAGCGGAAAGCAACCCCGACGGCAAAAAACAAAACAAACTTTTCCGTACCGAAGTCG
GCGCGGATGAAGTGGCCGAAATCGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGCGATAAA
TTGTTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGCCATCCG
CCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGGGTAAGA
CCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAATACATG
GAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGACCGAACA
AGTCCGCCGCAAACCGTACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCCTGCTGC
AAGTATTGGATGACGGCCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATGACTTCC
AACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGATGTGAA
AGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATATCCGCA
GTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGATGCCGCT
CTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGAAATCGA
AAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCGACAGAC
TGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-442)

• AAA domain (Cdc48 subfamily) (AAA_2) (599-761)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (767-847)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.837	100	0.44
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.186	100	0.398