Detailed information NTG0850306

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: QVX78_RS16775
• Genome accession: NZ_CP128992
• Coordinates: 3395078..3396241 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain ZLP-101
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3390078..3401241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QVX78_RS16745 (QVX78_16730)	-	3390342..3390761 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
QVX78_RS16750 (QVX78_16735)	comFC	3390835..3391524 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
QVX78_RS16755 (QVX78_16740)	-	3391530..3391814 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
QVX78_RS16760 (QVX78_16745)	comFA	3391872..3393257 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
QVX78_RS16765 (QVX78_16750)	-	3393366..3394214 (-)	849	WP_032876160.1	DegV family protein	-
QVX78_RS16770 (QVX78_16755)	degU	3394312..3395001 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
QVX78_RS16775 (QVX78_16760)	degS	3395078..3396241 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
QVX78_RS16780 (QVX78_16765)	-	3396464..3397111 (+)	648	WP_007614107.1	YigZ family protein	-
QVX78_RS16785 (QVX78_16770)	-	3397116..3398297 (+)	1182	WP_032876157.1	LCP family protein	-
QVX78_RS16790 (QVX78_16775)	-	3398396..3399472 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
QVX78_RS16795 (QVX78_16780)	-	3399605..3400801 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=850306 QVX78_RS16775 WP_007407484.1 3395078..3396241(-) (degS) [Bacillus velezensis strain ZLP-101]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=850306 QVX78_RS16775 WP_007407484.1 3395078..3396241(-) (degS) [Bacillus velezensis strain ZLP-101]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951