Detailed information NTG0850205

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: QWH96_RS10365
• Genome accession: NZ_CP128987
• Coordinates: 2067668..2070112 (-)
• Length: 814 a.a.
• NCBI ID: WP_003054754.1
• Uniprot ID: A0AAE9QRS9
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NS3396
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2062668..2075112

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QWH96_RS10345 (QWH96_10345)	-	2063026..2064522 (+)	1497	WP_015017475.1	C69 family dipeptidase	-
QWH96_RS10350 (QWH96_10350)	-	2064855..2065322 (+)	468	WP_003060031.1	8-oxo-dGTP diphosphatase	-
QWH96_RS10355 (QWH96_10355)	groL	2065539..2067164 (-)	1626	WP_042358011.1	chaperonin GroEL	-
QWH96_RS10360 (QWH96_10360)	groES	2067200..2067490 (-)	291	WP_003054738.1	co-chaperone GroES	-
QWH96_RS10365 (QWH96_10365)	clpC	2067668..2070112 (-)	2445	WP_003054754.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
QWH96_RS10370 (QWH96_10370)	-	2070112..2070573 (-)	462	WP_003054759.1	CtsR family transcriptional regulator	-
QWH96_RS10375 (QWH96_10375)	-	2070769..2070972 (-)	204	WP_003053018.1	cold-shock protein	-
QWH96_RS10380 (QWH96_10380)	-	2071473..2072285 (+)	813	WP_255304334.1	amidohydrolase family protein	-
QWH96_RS10385 (QWH96_10385)	-	2072417..2072872 (+)	456	WP_049519538.1	MarR family transcriptional regulator	-
QWH96_RS10390 (QWH96_10390)	-	2072974..2073393 (-)	420	WP_049519536.1	HD domain-containing protein	-
QWH96_RS10395 (QWH96_10395)	-	2073390..2073596 (-)	207	WP_015058115.1	hypothetical protein	-
QWH96_RS10400 (QWH96_10400)	-	2073598..2074842 (-)	1245	WP_015058116.1	phage head morphogenesis protein	-
QWH96_RS10405 (QWH96_10405)	-	2074843..2075106 (+)	264	Protein_2008	tyrosine-type recombinase/integrase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90381.04 Da
• Isoelectric Point: 6.7391

>NTDB_id=850205 QWH96_RS10365 WP_003054754.1 2067668..2070112(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKYQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAN
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSRPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNLE

Nucleotide

• Length: 2445 bp

>NTDB_id=850205 QWH96_RS10365 WP_003054754.1 2067668..2070112(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NS3396]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAGTTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGACCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGTCCTAAATACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCTACTCGCTTATTAGAGATGGCGGGTTATA
CTATCAAGGATAAAGGAAACGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGCAAG
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAAAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTGTCACGGATGATTCAAGTACTGAGTCGTAAAACAAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTACGGCCTAGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAGCTGCAAGA
CATGCGTGTTCTAGAATTAGACATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAAATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTATCATAATGTGACCATTGCTAAT
CAGGCTGTTAGAACCGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTGTT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGGCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGACATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCCTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
GAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTTGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAATACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAAAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTAGTCAAGATTATGGTGCAGCCGTTGATGGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTTAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTAC
GCCGCACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACCTTGAGTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (376-462)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.507	99.877	0.764
clpC	Streptococcus thermophilus LMD-9	72.794	100	0.73
clpC	Streptococcus thermophilus LMG 18311	72.794	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.159	99.877	0.671
clpC	Streptococcus pneumoniae Rx1	67.159	99.877	0.671
clpC	Streptococcus pneumoniae D39	67.159	99.877	0.671
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.681	100	0.499
clpC	Bacillus subtilis subsp. subtilis str. 168	42.84	100	0.437