Detailed information NTG0850117

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: V5G03_RS01250
• Genome accession: NZ_CP145077
• Coordinates: 248962..251811 (-)
• Length: 949 a.a.
• NCBI ID: WP_010951215.1
• Uniprot ID: Q5F7H1
• Organism: Neisseria gonorrhoeae strain WHO_G_2024
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 243962..256811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G03_RS01225 (V5G03_01235)	-	244244..245878 (+)	1635	WP_003689652.1	CTP synthase	-
V5G03_RS01230 (V5G03_01240)	-	246020..246673 (+)	654	WP_172617247.1	IS1595 family transposase	-
V5G03_RS01235 (V5G03_01245)	-	246670..246858 (-)	189	WP_014580099.1	transposase	-
V5G03_RS01240 (V5G03_01250)	-	247166..248299 (-)	1134	WP_003689650.1	DNA cytosine methyltransferase	-
V5G03_RS01245 (V5G03_01255)	-	248303..248944 (-)	642	WP_003689649.1	Eco29kI family restriction endonuclease	-
V5G03_RS01250 (V5G03_01260)	uvrA	248962..251811 (-)	2850	WP_010951215.1	excinuclease ABC subunit UvrA	Machinery gene
V5G03_RS01255 (V5G03_01265)	-	251965..252744 (+)	780	WP_003690682.1	phosphatidylserine decarboxylase	-
V5G03_RS01260 (V5G03_01270)	znuD	253284..255560 (-)	2277	WP_014580101.1	TonB-dependent zinc receptor ZnuD	-
V5G03_RS01265 (V5G03_01275)	-	255971..256561 (+)	591	WP_003689643.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 949 a.a.
• Molecular weight: 105477.17 Da
• Isoelectric Point: 7.0893

>NTDB_id=850117 V5G03_RS01250 WP_010951215.1 248962..251811(-) (uvrA) [Neisseria gonorrhoeae strain WHO_G_2024]
MCNHHPRHSHDNDTIRIRGARTHNLKNIDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMD
KPDVDLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVM
ILGPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGN
ERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLATGAIDGWD
KRNQFYFQMIQSLAHHYKFDVNVAWETLPEKVKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSE
TVREKLREYQNHRACPSCGGARLRKEARYVYVGGEPLHEVSAWPLTKTHRFFETLDLDGNKKQIAEKILKEITERLGFLI
NVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAI
READFVVDMGPGAGEHGGNVLIADTPENVAKCEKSVTGQYLGGKKSIAVPSERTPVNPGRMLVLKGARGNNLKNVTLELP
LGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYDDIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIR
ELFAGVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMT
VEEAREFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLL
EVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGKVIAKGSPEEVAKVKGSYTGKYLKVVLK

Nucleotide

• Length: 2850 bp

>NTDB_id=850117 V5G03_RS01250 WP_010951215.1 248962..251811(-) (uvrA) [Neisseria gonorrhoeae strain WHO_G_2024]
ATGTGCAACCATCATCCCCGACATTCGCACGACAACGACACCATCCGCATTCGCGGCGCGCGCACGCATAATTTGAAAAA
CATCGATTTGGACATTCCCCGCCACAAGCTCGTGGTGGTAACAGGATTGTCAGGCAGCGGCAAATCATCGCTGGCGTTTG
ATACTTTATATGCCGAAGGGCAGCGGCGTTATGTCGAGAGCCTGTCTGCCTATGCGCGGCAGTTTTTGCAGATGATGGAC
AAACCCGATGTCGATTTGATTGAAGGCCTGTCGCCTGCGATTTCCATCGAGCAGAAATCCACCAGCCACAATCCGCGTTC
CACCGTCGGCACGGTAACGGAAATCCACGACTACCTGCGCCTTTTATACGCCCGTGTCGGCACGCCGTATTGCCCCGAAC
ACAAGCTGCCGCTATCCAGCCAAACCGTATCTCAAATGGTCGATGCCGTATTAAAACTGCCGGAAGATACGCGCGTGATG
ATTCTGGGGCCGGCGGTGCGCGAGCGTAAGGGCGAGTTTGTCGATTTCTTTGCCGACTTGCAGGCGCAAGGCTTTGCCCG
TGTGCGCGTGGACGGCGAAGTCTATCAGCTTGACGAAGTACCGAAGCTGGAAAAAAACATCAAACACAATATCGACGTCG
TCATCGACCGCGTGAAAGTGAAAGCCGACATCAAACAACGACTGGCGGAAAGTTTTGAAACCGCGCTGCGCCACGGCAAC
GAGCGCGCGCTGGCGATGGAAATGGACAGCGGCGAAGAACATTGGTTTTCCGCGCGTTTTGCCTGCCCCGTATGCTCATA
CAGCCTGCCCGAATTGGAACCGCGCCTCTTTTCGTTCAACAACCCGATGGGTTCCTGCCCGACTTGCGACGGCTTGGGCA
ACACCAATTTCTTCGACCCCGAAAAAGTAGTCGCCCATCCCGAATTGTCGCTGGCAACCGGCGCGATTGACGGTTGGGAC
AAACGCAACCAATTCTATTTCCAAATGATTCAATCGCTGGCGCATCATTATAAATTTGATGTCAACGTCGCTTGGGAAAC
TTTGCCTGAAAAAGTCAAAAAAGTCGTGTTGCACGGCTCGGGCAAAGAAGTCATTGATTTCACCTACCTGTCCGAACGCG
GCACCACCTTCAACCGCAGCCACGCCTTCGAGGGCATCATCCCCAATCTCGAACGCCGCTACCGCGAAACCGACAGCGAA
ACCGTGCGCGAAAAACTGCGCGAGTACCAAAATCACCGTGCCTGCCCGAGCTGCGGCGGCGCACGTTTGCGCAAAGAAGC
ACGCTACGTTTACGTCGGCGGCGAACCGTTGCACGAAGTCTCCGCCTGGCCGCTGACCAAAACCCACCGATTCTTCGAAA
CGCTGGATTTGGACGGCAACAAAAAACAGATCGCCGAAAAAATCCTCAAAGAAATCACCGAGCGGCTCGGCTTCTTGATT
AACGTCGGGCTGGATTACCTGAATTTAAGCCGTTCCGCCGAAACCCTTTCCGGCGGCGAAGCCCAGCGCATCCGCCTCGC
CAGCCAAATCGGCAGCGGCCTGACCGGCGTGATGTACGTTTTGGACGAACCCTCCATCGGCCTGCACCAGCGCGACAACG
ACCGCCTGCTCGCCACCCTCAAACGCCTGCGCGATTTGGGCAACAGCGTAATTGTGGTCGAACACGACGAAGACGCCATC
CGCGAAGCCGATTTCGTCGTCGATATGGGCCCCGGCGCGGGCGAACACGGCGGCAACGTACTGATTGCCGACACACCCGA
AAATGTCGCCAAATGCGAAAAATCCGTTACCGGACAATACCTCGGCGGCAAAAAATCCATTGCCGTGCCGTCTGAACGCA
CGCCCGTCAATCCCGGCCGAATGCTCGTCCTCAAAGGTGCGCGCGGCAACAACCTCAAAAACGTCACCCTCGAGTTGCCG
CTCGGTTTGATTACCTGCATCACCGGCGTATCCGGCAGCGGCAAATCCACCCTGATTAACGACACCCTCGCCAAAATCAC
CGCCCGCGAACTCAACCGCGCCCAAGAAGAACCCGCCCCATACGACGACATCCGCGGCCTCGAACACCTCGACAAAGTCA
TCAACGTCGACCAATCCCCCATCGGCCGCACCCCGCGCTCCAACCCCGCCACCTACACCGGCCTGTTTACCCCCATCCGC
GAACTCTTCGCCGGCGTACCCCTCTCGCGCGAACGCGGCTACAACGTCGGCAGATTCTCCTTCAACGTCAAAGGCGGCCG
CTGCGAAGCCTGCCAAGGCGACGGCGTAATCAAAGTCGAAATGCACTTCCTGCCCGACGTGTACGTCCCCTGCGAAGTCT
GCCACGGCAAACGCTACAACCGCGAAACCCTCGAAATCCAATACAAAGGCAAAAACATCAGCCAAGTCCTCGACATGACG
GTCGAAGAAGCCCGCGAATTTTTCGACGCCGTCCCCACCGTATCGCGCAAACTGCAAACCCTGATGGACGTAGGTCTCGG
CTACATCCGCCTCGGCCAATCCGCCACCACCCTCTCCGGCGGCGAAGCCCAGCGCGTCAAACTCGCCTTGGAACTCTCCA
AACGCGACACCGGCAGAACGCTCTACATCCTCGACGAACCCACCACCGGCCTGCACTTCGCCGACATCGCCCTGCTGCTG
GAAGTCATAGGCCGTCTGAAAGGCAAAGGCAACTCGATTGTGATTATCGAGCATAATCTGGATGTAATTAAAACCGCGGA
TTGGATTGTGGACTTAGGGCCGGAAGGCGGCGATGGTGGGGGTAAGGTTATCGCGAAAGGTAGCCCTGAGGAAGTGGCGA
AGGTTAAGGGGAGTTATACCGGGAAGTATTTGAAAGTGGTTTTGAAGTAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (299-407)

• UvrA interaction domain (UvrA_inter) (141-245)

3D structure

• AlphaFold DB: Q5F7H1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	59.338	98.736	0.586
uvrA	Streptococcus pneumoniae TIGR4	59.338	98.736	0.586
uvrA	Streptococcus pneumoniae D39	59.338	98.736	0.586