Detailed information NTG0849572

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V5F99_RS05205
• Genome accession: NZ_CP145053
• Coordinates: 1009618..1012191 (+)
• Length: 857 a.a.
• NCBI ID: WP_047926685.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_beta_2024
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1004618..1017191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5F99_RS05185 (V5F99_05185)	ppx	1005344..1006852 (+)	1509	WP_003698289.1	exopolyphosphatase	-
V5F99_RS05190 (V5F99_05190)	-	1007062..1007406 (-)	345	WP_010360341.1	hypothetical protein	-
V5F99_RS05195 (V5F99_05195)	-	1007723..1008268 (-)	546	WP_003690987.1	hypothetical protein	-
V5F99_RS05200 (V5F99_05200)	trpS	1008348..1009358 (-)	1011	WP_003688198.1	tryptophan--tRNA ligase	-
V5F99_RS05205 (V5F99_05205)	clpC	1009618..1012191 (+)	2574	WP_047926685.1	ATP-dependent chaperone ClpB	Regulator
V5F99_RS05210 (V5F99_05210)	-	1012263..1013477 (-)	1215	WP_003695054.1	pyridoxal phosphate-dependent aminotransferase	-
V5F99_RS05215 (V5F99_05215)	-	1013566..1013775 (-)	210	WP_003688192.1	4-oxalocrotonate tautomerase family protein	-
V5F99_RS05220 (V5F99_05220)	-	1013967..1014773 (+)	807	WP_003704212.1	DUF4198 domain-containing protein	-
V5F99_RS05225 (V5F99_05225)	-	1014833..1016052 (-)	1220	Protein_1024	Glu/Leu/Phe/Val dehydrogenase	-
V5F99_RS05230 (V5F99_05230)	-	1016447..1017157 (+)	711	WP_003688188.1	phosphoglycolate phosphatase	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 94723.00 Da
• Isoelectric Point: 5.2460

>NTDB_id=849572 V5F99_RS05205 WP_047926685.1 1009618..1012191(+) (clpC) [Neisseria gonorrhoeae strain WHO_beta_2024]
MRYDKLTAKFQQALAEAQSLALAADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
IKMELDSKPEQMDKLDRRIIQLKMEKMHVAKESDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAASSSTADIKKQMD
DIKVKIEQAKRQGDFARASELEYGELPKLGAQLQAAESNPDGKKQNKLFRTEVGADEVAEIVSRMTGIPVSKMMEGERDK
LLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSEYM
EKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPHSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSDAA
LDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2574 bp

>NTDB_id=849572 V5F99_RS05205 WP_047926685.1 1009618..1012191(+) (clpC) [Neisseria gonorrhoeae strain WHO_beta_2024]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAATATCAATGCCGCGATCGATGCGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTTGGCGAACCCAGCGTGGAAGACACCAT
CGCTATCCTGCGCGGTTTGCAGGAACGTTACGAAATCCACCACGGCATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCCGACAAGGCGATTGATTTGATTGACGAAGCCGCCAGCCGC
ATCAAAATGGAGCTGGACAGCAAACCCGAACAGATGGACAAACTCGACCGCCGCATCATCCAGCTGAAAATGGAAAAAAT
GCACGTTGCCAAAGAAAGCGATGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAAGAAATCGACGGCCTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCCGCGTCTTCCAGCACTGCCGACATCAAGAAACAAATGGAC
GACATCAAAGTCAAAATCGAACAAGCCAAACGTCAAGGCGACTTCGCCCGCGCGTCCGAACTCGAATACGGCGAGTTGCC
GAAATTGGGCGCACAGTTGCAGGCAGCGGAAAGCAACCCCGACGGCAAAAAACAAAACAAACTTTTCCGTACCGAAGTCG
GCGCGGATGAAGTGGCCGAAATCGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGCGATAAA
TTGTTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGCCATCCG
CCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGGGTAAGA
CCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAATACATG
GAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGACCGAACA
AGTCCGCCGCAAACCGCACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCCTGCTGC
AAGTATTGGATGACGGTCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATGACTTCC
AACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGATGTGAA
AGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATATCCGCA
GTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGATGCCGCT
CTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGAAATCGA
AAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCGACAGAC
TGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-761)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (767-847)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (342-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.721	100	0.439
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.418	100	0.397
clpC	Lactococcus lactis subsp. cremoris KW2	44.524	80.98	0.361