Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   V5G18_RS06850 Genome accession   NZ_CP145045
Coordinates   1321481..1322146 (-) Length   221 a.a.
NCBI ID   WP_047921008.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_L_2024     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1316481..1327146
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G18_RS06815 (V5G18_06830) dut 1317143..1317595 (-) 453 WP_003702446.1 dUTP diphosphatase -
  V5G18_RS06820 (V5G18_06835) - 1317761..1318472 (+) 712 Protein_1327 AzlC family ABC transporter permease -
  V5G18_RS06825 (V5G18_06840) - 1318469..1318777 (+) 309 WP_047921007.1 AzlD family protein -
  V5G18_RS06830 (V5G18_06845) pilL 1318847..1319320 (-) 474 WP_172616930.1 PilX family type IV pilin Machinery gene
  V5G18_RS06835 (V5G18_06850) pilK 1319322..1319930 (-) 609 WP_047921003.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  V5G18_RS06840 (V5G18_06855) pilJ 1319909..1320844 (-) 936 WP_047921001.1 PilW family protein Machinery gene
  V5G18_RS06845 (V5G18_06860) pilV/pilI 1320841..1321449 (-) 609 WP_047920999.1 type IV pilus modification protein PilV Regulator
  V5G18_RS06850 (V5G18_06865) pilH 1321481..1322146 (-) 666 WP_047921008.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  V5G18_RS06855 (V5G18_06870) dnaB 1322454..1323860 (-) 1407 WP_047920816.1 replicative DNA helicase -
  V5G18_RS06860 (V5G18_06875) - 1324023..1324604 (+) 582 WP_003698180.1 superoxide dismutase -
  V5G18_RS06865 (V5G18_06880) - 1324834..1325343 (-) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  V5G18_RS06870 (V5G18_06885) - 1325670..1326002 (-) 333 WP_003687908.1 hypothetical protein -
  V5G18_RS06875 (V5G18_06890) cysT 1326188..1327026 (+) 839 Protein_1338 sulfate ABC transporter permease subunit CysT -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24628.98 Da        Isoelectric Point: 8.8946

>NTDB_id=849284 V5G18_RS06850 WP_047921008.1 1321481..1322146(-) (pilH) [Neisseria gonorrhoeae strain WHO_L_2024]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNGNKAYDGDVADVFLRSVVLNDDINDKRIDYAFNHIAFGSSQPTADRVVWTFNQNGTFGYTT
DQHLTERSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH

Nucleotide


Download         Length: 666 bp        

>NTDB_id=849284 V5G18_RS06850 WP_047921008.1 1321481..1322146(-) (pilH) [Neisseria gonorrhoeae strain WHO_L_2024]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TTTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGCATATGACGGCGA
TGTGGCGGATGTTTTCCTCCGCAGCGTGGTATTGAATGATGATATCAATGATAAGCGGATTGATTATGCCTTCAACCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACGTTCAATCAAAACGGGACGTTCGGTTATACGACA
GACCAGCATCTTACAGAGCGATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA

Domains

Predicted by InterProScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

90.95

100

0.91