Detailed information NTG0848775

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V5G17_RS05900
• Genome accession: NZ_CP145024
• Coordinates: 1140947..1143526 (+)
• Length: 859 a.a.
• NCBI ID: WP_106333486.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_U_2024
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1135947..1148526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G17_RS05880 (V5G17_05885)	-	1136672..1138180 (+)	1509	WP_003690989.1	Ppx/GppA phosphatase family protein	-
V5G17_RS05885 (V5G17_05890)	-	1138390..1138734 (-)	345	WP_010358382.1	hypothetical protein	-
V5G17_RS05890 (V5G17_05895)	-	1139051..1139596 (-)	546	WP_003690987.1	hypothetical protein	-
V5G17_RS05895 (V5G17_05900)	trpS	1139677..1140687 (-)	1011	WP_003690986.1	tryptophan--tRNA ligase	-
V5G17_RS05900 (V5G17_05905)	clpC	1140947..1143526 (+)	2580	WP_106333486.1	ATP-dependent chaperone ClpB	Regulator
V5G17_RS05905 (V5G17_05910)	-	1143598..1144812 (-)	1215	WP_003690983.1	pyridoxal phosphate-dependent aminotransferase	-
V5G17_RS05910 (V5G17_05915)	-	1144901..1145110 (-)	210	WP_003688192.1	4-oxalocrotonate tautomerase family protein	-
V5G17_RS05915 (V5G17_05920)	-	1145302..1146108 (+)	807	WP_003690982.1	DUF4198 domain-containing protein	-
V5G17_RS05920 (V5G17_05925)	-	1146168..1147387 (-)	1220	Protein_1157	Glu/Leu/Phe/Val dehydrogenase	-
V5G17_RS05925 (V5G17_05930)	-	1147782..1148492 (+)	711	WP_003690977.1	phosphoglycolate phosphatase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95082.50 Da
• Isoelectric Point: 5.3682

>NTDB_id=848775 V5G17_RS05900 WP_106333486.1 1140947..1143526(+) (clpC) [Neisseria gonorrhoeae strain WHO_U_2024]
MRYDKLTAKFQQALAEAQSLALAADSSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGE
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEIDGLQKEYADLDEIWKAEKAISNGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGADEVAEIVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQNEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIKVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=848775 V5G17_RS05900 WP_106333486.1 1140947..1143526(+) (clpC) [Neisseria gonorrhoeae strain WHO_U_2024]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAAGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACAGCAG
CTATCTGGAAGCAGGTTTCGTACTGAAAGCCCTGCTTGACGACCAAAACAGCGGAGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTTAAACAGCGTTTGCAGCAGCATTTGAATAGCCTGCCGAAAGTGTCCGGACAAGGTGGTGAG
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCGGCAACCAAACGCGGCGATGCCTATATCGC
CAGCGAACTTTTCCTGCTCGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATCTTGAAAGAAGCCGGTGCGACCGAAC
AAAACATCAATGCCGCGATCGATGCGGTACGAGGCGGACAAAACGTGAACGATGCGAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATACACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGTCGTGATGATGAAAT
CCGCCGCGCGATTCAGGTGCTGCAACGCCGCACCAAAAACAACCCCGTGCTGATTGGCGAACCCGGTGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCGCAACGCATCGTCAACGGCGAAGTACCTGAATCCCTGCGTAACAAACGCCTGCTGGTTTTG
GATTTGGCGGCTTTGATTGCCGGTGCGAAATACCGTGGCGAATTTGAAGAACGCTTGAAAGGCGTATTGAACGATTTGGC
GAAAGACGACGGCAACACCCTGATTTTCATCGATGAAATCCATACTTTGGTCGGCGCGGGCAAAACCGACGGCGCGATGG
ACGCGGGCAATATGTTGAAACCGGCCTTGGCGCGGGGCGAACTGCACTGTATCGGTGCGACTACTTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGTTTCCAAAAAGTATTGGTCGGCGAACCCAGCGTGGAAGACACCAT
CGCTATCCTGCGCGGTTTGCAGGAACGCTATGAAATCCACCACGGCATCGATATTACCGACCCCGCCATTGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTTTTGCCCGACAAGGCGATTGATTTGATTGACGAAGCTGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAACCGGAAGCTATGGACAAAATCGACCGCCGTTTGATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCGACGGCTTGCAAAAAG
AATACGCCGATTTGGACGAAATCTGGAAAGCCGAAAAAGCGATTTCAAACGGTGCTGCCAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCGGATGAAGTGGCCGAAATCGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GATAAATTGTTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAAACGAAGCCGTGCGCGCCGTGTCCGATGC
CATCCGCCGCAGCCGCTCCGGCCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTAGGCCCGACCGGTGTGG
GTAAGACCGAGTTGTGCAAAGCTTTGGCAGGCTTCCTGTTCGACAGCGAAGACCACCTCATCCGCATCGACATGTCCGAA
TACATGGAAAAACACGCCGTTGCCCGCTTAATCGGCGCGCCTCCGGGTTATGTCGGATACGAAGAGGGCGGCTACCTGAC
CGAACAAGTCCGCCGCAAACCGTACAGCGTGATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGACGTATTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCACGCAGGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCGGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCATGGCTTGGATCAGGCCAATA
TCCGCAGTATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCTCTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCGATCCAATCGGA
AATCGAAAACCCGCTGGCCAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAAGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-442)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.554	100	0.437
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.335	100	0.42
clpC	Streptococcus pneumoniae D39	39.092	100	0.411
clpC	Streptococcus pneumoniae TIGR4	39.092	100	0.411
clpC	Streptococcus pneumoniae Rx1	39.092	100	0.411
clpC	Lactococcus lactis subsp. cremoris KW2	46.839	81.024	0.38
clpE	Streptococcus pneumoniae TIGR4	46.921	79.395	0.373
clpE	Streptococcus pneumoniae D39	46.774	79.395	0.371
clpE	Streptococcus pneumoniae R6	46.774	79.395	0.371
clpE	Streptococcus pneumoniae Rx1	46.774	79.395	0.371